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Table 4 Antigens that showed significant IgG response at day 40 in mice infected with tissue cysts

From: Discovery of new Toxoplasma gondii antigenic proteins using a high throughput protein microarray approach screening sera of murine model infected orally with oocysts and tissue cysts

Rank a

Gene ID_exon

Description

Benjamini-Hochberg corrected P-value (d0 vs d40)

1

TGME49_070240_3

Unspecified product (MAG1)

P = 0.0006

2

TGME49_003310_1

Dense granule protein GRA7

P = 0.0017

3

TGME49_075440_1

Granule antigen protein GRA6

P = 0.0006

4

TGME49_109590_1

Rhoptry protein 1

P = 0.0006

5

TGME49_054720_1

Dense granule protein GRA8

P = 0.0006

6

TGME49_086450_1

Dense granule protein 5 precursor

P = 0.0006

7

TGME49_110780_1

Dense granule protein GRA4

P = 0.0092

8

TGME49_021710_4

TBC domain-containing protein

P = 0.0180

9

TGME49_001780_2

Microneme protein MIC2

P = 0.0037

10

TGME49_027280_1

Dense granule protein GRA3

P = 0.0006

11

TGME49_022370_1

SAG-related sequence SRS13

P = 0.0187

12

TGME49_033450_1

SAG-related sequence SRS29A

P = 0.0475

13

TGME49_027620_2

Dense granule protein GRA2

P = 0.0092

14

TGME49_067680_8

Microneme protein MIC12

P = 0.0187

15

TGME49_004050_8

Subtilisin SUB1

P = 0.0317

16

TGME49_039740_1

Dense granule protein GRA14

P = 0.0006

17

TGME49_033480_1

SAG-related sequence SRS29C

P = 0.0477

18

TGME49_091890_4

Microneme protein MIC1

P = 0.0354

19

TGME49_015980_1

Hypothetical protein

P = 0.0010

20

TGME49_088380_4

Heat shock protein HSP90

P = 0.0012

21

TGME49_119340_2

Hypothetical protein

P = 0.0280

22

TGME49_013390_5

Plectin, putative

P = 0.0370

23

TGME49_058660_2

Rhoptry protein ROP6

P = 0.0355

24

TGME49_070250_2

Dense granule protein GRA1

P = 0.0388

25

TGME49_010090_1

Protein kinase domain-containing protein

P = 0.0354

26

TGME49_090720_12

Vacuolar proton translocating ATPase subunit, putative

P = 0.0297

27

TGME49_026020_8

Transporter, major facilitator family protein

P = 0.0485

28

TGME49_075490_8

Hypothetical protein

P = 0.0388

29

TGME49_033530_1

Hypothetical protein

P = 0.0099

30

TGME49_115250_2

GAMM1 protein, putative

P = 0.0485

31

TGME49_106310_7

RecF/RecN/SMC N terminal domain-containing protein

P = 0.0187

32

TGME49_105020_6

Hypothetical protein

P = 0.0387

33

TGME49_057080_5

3'5'-cyclic nucleotide phosphodiesterase domain-containing protein

P = 0.0408

34

TGME49_093730_6

DHHC zinc finger domain-containing protein

P = 0.0108

35

TGME49_113020_9

STAS domain-containing protein

P = 0.0134

36

TGME49_031430_2

Oligosaccharyl transferase stt3 protein, putative

P = 0.0365

37

TGME49_026660_8

Hypothetical protein

P = 0.0187

38

TGME49_048200_4

Ribosomal RNA- dimethyltransferase, putative

P = 0.0488

39

TGME49_001390_1

Hypothetical protein

P = 0.0180

40

TGME49_090010_1

Hypothetical protein

P = 0.0485

  1. aBased on average signal value, as per Figs. 7 and 8