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Table 4 Antigens that showed significant IgG response at day 40 in mice infected with tissue cysts

From: Discovery of new Toxoplasma gondii antigenic proteins using a high throughput protein microarray approach screening sera of murine model infected orally with oocysts and tissue cysts

Rank a Gene ID_exon Description Benjamini-Hochberg corrected P-value (d0 vs d40)
1 TGME49_070240_3 Unspecified product (MAG1) P = 0.0006
2 TGME49_003310_1 Dense granule protein GRA7 P = 0.0017
3 TGME49_075440_1 Granule antigen protein GRA6 P = 0.0006
4 TGME49_109590_1 Rhoptry protein 1 P = 0.0006
5 TGME49_054720_1 Dense granule protein GRA8 P = 0.0006
6 TGME49_086450_1 Dense granule protein 5 precursor P = 0.0006
7 TGME49_110780_1 Dense granule protein GRA4 P = 0.0092
8 TGME49_021710_4 TBC domain-containing protein P = 0.0180
9 TGME49_001780_2 Microneme protein MIC2 P = 0.0037
10 TGME49_027280_1 Dense granule protein GRA3 P = 0.0006
11 TGME49_022370_1 SAG-related sequence SRS13 P = 0.0187
12 TGME49_033450_1 SAG-related sequence SRS29A P = 0.0475
13 TGME49_027620_2 Dense granule protein GRA2 P = 0.0092
14 TGME49_067680_8 Microneme protein MIC12 P = 0.0187
15 TGME49_004050_8 Subtilisin SUB1 P = 0.0317
16 TGME49_039740_1 Dense granule protein GRA14 P = 0.0006
17 TGME49_033480_1 SAG-related sequence SRS29C P = 0.0477
18 TGME49_091890_4 Microneme protein MIC1 P = 0.0354
19 TGME49_015980_1 Hypothetical protein P = 0.0010
20 TGME49_088380_4 Heat shock protein HSP90 P = 0.0012
21 TGME49_119340_2 Hypothetical protein P = 0.0280
22 TGME49_013390_5 Plectin, putative P = 0.0370
23 TGME49_058660_2 Rhoptry protein ROP6 P = 0.0355
24 TGME49_070250_2 Dense granule protein GRA1 P = 0.0388
25 TGME49_010090_1 Protein kinase domain-containing protein P = 0.0354
26 TGME49_090720_12 Vacuolar proton translocating ATPase subunit, putative P = 0.0297
27 TGME49_026020_8 Transporter, major facilitator family protein P = 0.0485
28 TGME49_075490_8 Hypothetical protein P = 0.0388
29 TGME49_033530_1 Hypothetical protein P = 0.0099
30 TGME49_115250_2 GAMM1 protein, putative P = 0.0485
31 TGME49_106310_7 RecF/RecN/SMC N terminal domain-containing protein P = 0.0187
32 TGME49_105020_6 Hypothetical protein P = 0.0387
33 TGME49_057080_5 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein P = 0.0408
34 TGME49_093730_6 DHHC zinc finger domain-containing protein P = 0.0108
35 TGME49_113020_9 STAS domain-containing protein P = 0.0134
36 TGME49_031430_2 Oligosaccharyl transferase stt3 protein, putative P = 0.0365
37 TGME49_026660_8 Hypothetical protein P = 0.0187
38 TGME49_048200_4 Ribosomal RNA- dimethyltransferase, putative P = 0.0488
39 TGME49_001390_1 Hypothetical protein P = 0.0180
40 TGME49_090010_1 Hypothetical protein P = 0.0485
  1. aBased on average signal value, as per Figs. 7 and 8