Fig. 2
From: Leishmaniasis and glycosaminoglycans: a future therapeutic strategy?
Glycosaminoglycans as a therapeutic strategy. a Heparin-binding protein from Leishmania spp. recognizes and binds to glycosaminoglycans (GAGs) in the surface of macrophages. This recognition is important for parasite binding to and infection of macrophages. b Exogenous GAGs may interfere with this interaction, decreasing macrophage infection and parasite dissemination/survival