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Table 2 ANCOVA analysis for non-inferiority testing - live attached tick counts (PP)

From: A randomized, controlled field study to assess the efficacy and safety of lotilaner (Credelio™) in controlling ticks in client-owned cats in Europe

Day Lotilaner (n = 112) Fipronil (n = 57) Comparison 95% CI
Geometric mean tick count Est SE Geometric mean tick count Est SE t-value P-valuea
0 3.60 na na 3.52 na na
7 0.00 0.00 0.01 0.01 0.01 0.01 t(162) = 1.32 0.1876 0.97–1.01
14 0.00 0.00 0.01 0.04 0.05 0.02 t(164) = 2.08 0.0394 0.92–1.00
21 0.00 0.01 0.02 0.09 0.10 0.03 t(164) = 2.82 0.0054 086–0.97
28 0.06 0.06 0.04 0.37 0.35 0.07 t(162) = 4.04 < 0.0001 0.69–0.88
42 0.00 0.00 0.03 0.22 0.22 0.04 t(163) = 4.53 < 0.0001 0.75–0.89
56 0.04 0.03 0.03 0.22 0.21 0.05 t(162) = 3.25 0.0014 0.78–0.94
70 0.01 0.01 0.02 0.11 0.10 0.03 t(160) = 2.42 0.0167 0.85–0.98
84 0.00 0.00 0.01 0.01 0.01 0.01 t(159) = 1.36 0.1747 0.97–1.01
Mean 0.01 0.02 0.02 0.13 0.18 0.03 t(164) = 5.16 < 0.0001 0.82–0.91
  1. Abbreviations: Est, estimate; na, not applicable; SE, standard error
  2. aSignificant values (P < 0.05) in bold