Table 2 ANCOVA analysis for non-inferiority testing - live attached tick counts (PP)
Day | Lotilaner (n = 112) | Fipronil (n = 57) | Comparison | 95% CI | |||||
|---|---|---|---|---|---|---|---|---|---|
Geometric mean tick count | Est | SE | Geometric mean tick count | Est | SE | t-value | P-valuea | ||
0 | 3.60 | na | na | 3.52 | na | na | – | – | – |
7 | 0.00 | 0.00 | 0.01 | 0.01 | 0.01 | 0.01 | t(162) = 1.32 | 0.1876 | 0.97–1.01 |
14 | 0.00 | 0.00 | 0.01 | 0.04 | 0.05 | 0.02 | t(164) = 2.08 | 0.0394 | 0.92–1.00 |
21 | 0.00 | 0.01 | 0.02 | 0.09 | 0.10 | 0.03 | t(164) = 2.82 | 0.0054 | 086–0.97 |
28 | 0.06 | 0.06 | 0.04 | 0.37 | 0.35 | 0.07 | t(162) = 4.04 | < 0.0001 | 0.69–0.88 |
42 | 0.00 | 0.00 | 0.03 | 0.22 | 0.22 | 0.04 | t(163) = 4.53 | < 0.0001 | 0.75–0.89 |
56 | 0.04 | 0.03 | 0.03 | 0.22 | 0.21 | 0.05 | t(162) = 3.25 | 0.0014 | 0.78–0.94 |
70 | 0.01 | 0.01 | 0.02 | 0.11 | 0.10 | 0.03 | t(160) = 2.42 | 0.0167 | 0.85–0.98 |
84 | 0.00 | 0.00 | 0.01 | 0.01 | 0.01 | 0.01 | t(159) = 1.36 | 0.1747 | 0.97–1.01 |
Mean | 0.01 | 0.02 | 0.02 | 0.13 | 0.18 | 0.03 | t(164) = 5.16 | < 0.0001 | 0.82–0.91 |