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Table 5 Geometric (arithmetic) mean counts of live, female I. ricinus ticks and percent efficacy of lotilaner against infestations present at the time of treatment

From: Laboratory evaluation of the efficacy and speed of kill of lotilaner (CredelioTM) against Ixodes ricinus ticks on cats

Time post-treatment

Untreated control

Lotilaner

Comparison

Mean

Range

Mean

Range

Efficacy (%)

t-value

P-value

12 h Pre-incubation

14.58 (15.63)

9–26

1.14 (1.75)

0–5

92.2 (88.8)

t(7) = 7.6

0.0001

Post-incubation

14.48 (15.50)

9–26

0.25 (0.38)

0–2

98.3 (97.6)

t(7) = 13.1

< 0.0001

18 h Pre-incubation

15.36 (16.75)

7–26

0.19 (0.25)

0–1

98.8 (98.5)

t(7) = 14.4

< 0.0001

Post-incubation

15.21 (16.63)

7–26

0.09 (0.13)

0–1

99.4 (99.2)

t(7) = 17.4

< 0.0001

24 h Pre-incubation

12.56 (13.13)

6–18

0 (0)

0–0

100 (100)

t(7) = 22.8

< 0.0001

Post-incubation

12.56 (3.13)

6–18

0 (0)

0–0

100 (100)

t(7) = 22.8

< 0.0001