Laboratory evaluation of the efficacy and speed of kill of lotilaner (CredelioTM) against Ixodes ricinus ticks on cats

Table 8 Geometric (arithmetic) mean counts of live, female I. ricinus ticks and % efficacy of lotilaner, 24 hours after post-treatment infestations

Day^a	Time-point	Untreated control		Lotilaner			Comparison
Day^a	Time-point	Mean	Range	Mean	Range	Efficacy (%)	t-value	P-value
7	Pre-incubation	16.94 (17.50)	9–24	0 (0)	0–0	100 (100)	t₍₇₎ = 29.5	< 0.0001
7	Post-incubation	16.94 (17.50)	9–24	0 (0)	0–0	100 (100)	t₍₇₎ = 29.5	< 0.0001
14	Pre-incubation	13.96 (15.25)	6–27	0 (0)	0–0	100 (100)	t₍₇₎ = 17.3	< 0.0001
14	Post-incubation.	13.89 (15.13)	6–26	0 (0)	0–0	100 (100)	t₍₇₎ = 17.5	< 0.0001
21	Pre-incubation	15.93 (17.63)	5–29	0 (0)	0–0	100 (100)	t₍₇₎ = 15.8	< 0.0001
21	Post-incubation.	15.93 (17.63)	5–29	0 (0)	0–0	100 (100)	t₍₇₎ = 15.8	< 0.0001
28	Pre-incubation	13.00 (13.50)	9–20	0.15 (0.25)	0–2	98.9 (98.1)	t₍₇₎ = 14.8	< 0.0001
28	Post-incubation.	13.00 (13.50)	9–20	0.09 (0.35)	0–0	99.1 (99.3)	t₍₇₎ = 19.4	< 0.0001
35	Pre-incubation	12.85 (13.88)	6–24	0 (0)	0–0	100 (100)	t₍₇₎ = 18.1	< 0.0001
35	Post-incubation	12.76 (13.75)	6-24	0 (0)	0–0	100 (100)	t₍₇₎ = 18.4	< 0.0001

ISSN: 1756-3305