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Table 1 Demographics and baseline characteristics of the enrolled animals (ITT population)

From: A randomized, controlled field study to assess the efficacy and safety of lotilaner (Credelio™) in controlling fleas in client-owned cats in Europe

   Lotilaner-treated animals (n = 121) Fipronil/(S)-methoprene-treated animals (n = 61) Comparison
     Z-valuea/ χ2-valuea/ t-value P-value
Age (years) Mean ± SD 3.49 ± 3.12 3.42 ± 3.57 Z = 0.452 0.6510
Range 0.17–13.0 0.17–14.0   
Weight (kg) Mean ± SD 3.8 ± 1.5 3.9 ± 1.7 Z = 0.267 0.7896
Range 1.0–8.7 1.1–8.0   
Sex Male 69 (57%) 36 (59%) Z = 0.254 0.8741
Female 52 (43%) 25 (41%)
Breed European 29 (24%) 9 (15%) χ2 = 12.30, df = 7 0.0911
Persian 4 (3%) 2 (3%)
Siamese 0 (0%) 4 (7%)
Maine Coon 2 (2%) 0 (0%)
Ragdoll 1 (1%) 0 (0%)
Chartreuse 1 (1%) 0 (0%)
Selkirk rex 1 (1%) 0 (0%)
Crossbreeds 83 (69%) 46 (75%)
Animal spends time Mostly indoors 48 (40%) 19 (31%) χ2 = 2.66, df = 2 0.2650
Indoors and outdoors 56 (46%) 36 (59%)
Mostly outdoors 17 (14%) 6 (10%)
No. of cats in household 1 52 (43%) 31 (51%) Z = 0.900 0.3680
2 42 (35%) 18 (30%)
3 27 (22%) 12 (20%)
Mean ± SD 1.8 ± 0.8 1.7 ± 0.8
Range 1.0–3.0 1.0–3.0
Hair length Short 76 (63%) 42 (69%) Z = 0.991 0.3216
Medium 27 (22%) 14 (23%)
Long 18 (15%) 5 (8%)
Day 0 flea count Mean ± SD 15.75 ± 17.54 16.92 ± 18.22 t(178) = 0.50 0.6159
  1. aZ of a Mann-Whitney test; χ2 of a Kruskal-Wallis test (of treatment vs breed); df, degrees of freedom; t(df), ANOVA t-statistic with df degrees of freedom
  2. Abbreviation: SD standard deviation