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Table 2 Mean flea counts in control and lotilaner-treated animals and % efficacy at 24 hours post-treatment and 24 hours after weekly infestations (Study 1)

From: Laboratory evaluation of the efficacy and speed of kill of lotilaner (Credelio™) against Ctenocephalides felis on cats

  Day of infestation and flea count
0 7 14 21 28 35
Control
(n = 8)
Arithmetic mean ± SD 67.3 ± 14.3 85.4 ± 8.7 79.6 ± 10.7 75.1 ± 12.2 71.4 ± 10.3 84.4 ± 11.4
Geometric mean ± SD 65.8 ± 15.1 85.0 ± 8.8 79.0 ± 10.8 74.2 ± 12.9 70.8 ± 10.0 83.7 ± 12.2
Lotilaner
(n = 8)
Arithmetic mean ± SD 0.0 ± 0.0 0.0 ± 0.0 0.0 ± 0.0 0.0 ± 0.0 0.0 ± 0.0 0.0 ± 0.0
Efficacy (%) 100 100 100 100 100 100
Geometric mean ± SD 0.0 ± 0.0 0.0 ± 0.0 0.0 ± 0.0 0.0 ± 0.0 0.0 ± 0.0 0.0 ± 0.0
Efficacy (%) 100 100 100 100 100 100
Comparison t(13) = 57.1,
P < 0.0001
t(13) = 136.9,
P < 0.0001
t(13) = 99.9,
P < 0.0001
t(13) = 71.7,
P < 0.0001
t(13) = 86.8,
P < 0.0001
t(13) = 87.3,
P < 0.0001