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Table 2 Mean flea counts in control and lotilaner-treated animals and % efficacy at 24 hours post-treatment and 24 hours after weekly infestations (Study 1)

From: Laboratory evaluation of the efficacy and speed of kill of lotilaner (Credelio™) against Ctenocephalides felis on cats

 

Day of infestation and flea count

0

7

14

21

28

35

Control

(n = 8)

Arithmetic mean ± SD

67.3 ± 14.3

85.4 ± 8.7

79.6 ± 10.7

75.1 ± 12.2

71.4 ± 10.3

84.4 ± 11.4

Geometric mean ± SD

65.8 ± 15.1

85.0 ± 8.8

79.0 ± 10.8

74.2 ± 12.9

70.8 ± 10.0

83.7 ± 12.2

Lotilaner

(n = 8)

Arithmetic mean ± SD

0.0 ± 0.0

0.0 ± 0.0

0.0 ± 0.0

0.0 ± 0.0

0.0 ± 0.0

0.0 ± 0.0

Efficacy (%)

100

100

100

100

100

100

Geometric mean ± SD

0.0 ± 0.0

0.0 ± 0.0

0.0 ± 0.0

0.0 ± 0.0

0.0 ± 0.0

0.0 ± 0.0

Efficacy (%)

100

100

100

100

100

100

Comparison

t(13) = 57.1,

P < 0.0001

t(13) = 136.9,

P < 0.0001

t(13) = 99.9,

P < 0.0001

t(13) = 71.7,

P < 0.0001

t(13) = 86.8,

P < 0.0001

t(13) = 87.3,

P < 0.0001