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Table 1 Flea counts on naturally infested cats in households in Florida before and after treatment with either a single topical dose of fluralaner or three consecutive monthly doses of selamectin

From: In-home assessment of either topical fluralaner or topical selamectin for flea control in naturally infested cats in West Central Florida, USA

Treatment group

No. of cats on day 0

 

Days post-treatment

0

7

14

21

28–30

40-45

56-60

82-86

Fluralaner1

31

Geomean flea count3

11.4a,x

0.4b,y

0.3b,y

0.1b,y

0.2b,y

0.1b,y

0.1b,y

0.0b,y

Range

(5–63)

(0–4)

(0–4)

(0–3)

(0–2)

(0–2)

(0–3)

(0–0)

% control4

 

96.6

97.3

99.3

98.5

99.5

99.2

100

% (#) cats with no fleas

0.0a,x (0/31)

69.0b,y (20/29)

71.0b,y (22/31)

93.5b,y

(29/31)

80.6b,y

(25/31)

93.5b,y

(29/31)

90.3b,y

(28/31)

100b,y

(31/31)

Selamectin2

29

Geomean flea count3

12.7a,x

2.6a,y

3.2a,y

3.6a,y

2.8a,y

0.8a,y

1.1a,y

1.1a,y

Range

(5–44)

(0–23)

(0–29)

(0–50)

(0–35)

(0–14)

(0–11)

(0–8)

% control4

 

79.4

74.6

71.3

77.8

93.8

91.0

91.3

% (#) cats with no fleas

0.0a,x

(0/29)

24.1a,y

(7/29)

28.6a,y

(8/28)

17.2a,x

(5/29)

17.2a,x

(5/29)

37.0a,y

(10/27)

44.4a,y

(12/27)

38.5a,y

(10/26)

  1. 1In the fluralaner group cats were treated once topically on day 0 (Bravecto® Topical solution; Merck Animal Health, Madison, NJ, USA)
  2. 2In the selamectin group cats were treated on day 0 and once between days 28–30 and 56–60 (Revolution®; Zoetis, Whippany, NJ, USA)
  3. 3Geometric mean numbers of fleas in comb counts
  4. 4{(Day 0 geometric mean animal area flea counts – day x geometric mean animal area flea counts) / day 0 geometric mean animal area flea counts)} × 100
  5. a,bGeometric mean flea counts in a column with unlike letter superscripts are significantly different (P < 0.001; │t│≥ 3.70)
  6. x,yGeometric mean flea counts in a row with unlike letter superscripts are significantly different from day 0 (P < 0.001; │t│≥ 7.14)
  7. a,bPercent of flea-free cats in a column with unlike letter superscripts are significantly different (P < 0.002; Fisher’s exact test)
  8. x,yPercent of flea- free cats in a row with unlike letter superscripts are significantly different from day 0 (P < 0.01; Fisher’s exact test)