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Table 1 Flea counts on naturally infested cats in households in Florida before and after treatment with either a single topical dose of fluralaner or three consecutive monthly doses of selamectin

From: In-home assessment of either topical fluralaner or topical selamectin for flea control in naturally infested cats in West Central Florida, USA

Treatment group No. of cats on day 0   Days post-treatment
0 7 14 21 28–30 40-45 56-60 82-86
Fluralaner1 31 Geomean flea count3 11.4a,x 0.4b,y 0.3b,y 0.1b,y 0.2b,y 0.1b,y 0.1b,y 0.0b,y
Range (5–63) (0–4) (0–4) (0–3) (0–2) (0–2) (0–3) (0–0)
% control4   96.6 97.3 99.3 98.5 99.5 99.2 100
% (#) cats with no fleas 0.0a,x (0/31) 69.0b,y (20/29) 71.0b,y (22/31) 93.5b,y
(29/31)
80.6b,y
(25/31)
93.5b,y
(29/31)
90.3b,y
(28/31)
100b,y
(31/31)
Selamectin2 29 Geomean flea count3 12.7a,x 2.6a,y 3.2a,y 3.6a,y 2.8a,y 0.8a,y 1.1a,y 1.1a,y
Range (5–44) (0–23) (0–29) (0–50) (0–35) (0–14) (0–11) (0–8)
% control4   79.4 74.6 71.3 77.8 93.8 91.0 91.3
% (#) cats with no fleas 0.0a,x
(0/29)
24.1a,y
(7/29)
28.6a,y
(8/28)
17.2a,x
(5/29)
17.2a,x
(5/29)
37.0a,y
(10/27)
44.4a,y
(12/27)
38.5a,y
(10/26)
  1. 1In the fluralaner group cats were treated once topically on day 0 (Bravecto® Topical solution; Merck Animal Health, Madison, NJ, USA)
  2. 2In the selamectin group cats were treated on day 0 and once between days 28–30 and 56–60 (Revolution®; Zoetis, Whippany, NJ, USA)
  3. 3Geometric mean numbers of fleas in comb counts
  4. 4{(Day 0 geometric mean animal area flea counts – day x geometric mean animal area flea counts) / day 0 geometric mean animal area flea counts)} × 100
  5. a,bGeometric mean flea counts in a column with unlike letter superscripts are significantly different (P < 0.001; │t│≥ 3.70)
  6. x,yGeometric mean flea counts in a row with unlike letter superscripts are significantly different from day 0 (P < 0.001; │t│≥ 7.14)
  7. a,bPercent of flea-free cats in a column with unlike letter superscripts are significantly different (P < 0.002; Fisher’s exact test)
  8. x,yPercent of flea- free cats in a row with unlike letter superscripts are significantly different from day 0 (P < 0.01; Fisher’s exact test)