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Table 3 Fleas caught in intermittent-light flea traps in naturally infested homes in Florida before and after treatment of all dogs and cats in the homes with either a single administration of fluralaner or three consecutive monthly administrations of sarolaner (dogs) and selamectin (cats)

From: In-home assessment of either topical fluralaner or topical selamectin for flea control in naturally infested cats in West Central Florida, USA

Treatment group Days post-treatment
   0 7 14 21 28–30 40–45 56–60 82–86
Fluralaner1 20 homes on study          
Geomean flea count3 32.4a,x 6.3a,y 7.2a,y 1.6b,y 0.5a,y 0.2a,y 0.1a,y 0.04a,y
Range (5–183) (0–113) (0–156) (0–19) (0–6) (0–5) (0–1) (0–1)
% control4   80.4 77.9 95.0 98.4 99.4 99.8 99.9
% (#) homes with 0 fleas in traps 0.0a,x (0/20) 10.5a,x (2/19) 20.0a,x (4/20) 30.0a,y (6/20) 70.0a,y (14/20) 85.0a,y (17/20 90.0a,y (18/20) 95.0a,y (19/20)
% (#) homes with no fleas (traps, cats or dogs) 0.0a,x (0/20) 15.0a,x (3/20) 15.0a,x (3/20) 30.0b,y (6/20) 60.0b,y (12/20) 75.0b,y (15/20) 80.0b,y (16/20) 95.0b,y (19/20)
Selamectin/Sarolaner2 18 homes on study Geomean flea count3 28.0a,x 4.7a,y 4.8a,y 4.2a,y 1.4a,y 0.04a,y 0.4a,y 0.4a,y
Range (5–152) (0–195) (0–93) (0–22) (0–1) (0–14) (0–39) (0–12)
% control4   83.1 82.7 85.0 95.1 99.9 98.8 98.5
% (#) homes with 0 fleas in traps 0.0a,x (0/18) 16.7a,x (3/18) 17.6a,x (3/17) 22.2a,x (4/18) 44.4a,y (8/18) 94.1a,y (16/17) 82.4a,y (14/17) 68.8a,y (11/16)
% (#) homes with no fleas (traps, cats or dogs) 0.0a,x (0/18) 5.6a,x (1/18) 16.7a,x (3/18) 0.0a,x (0/18) 5.6a,x (1/18) 23.5a,y (4/17) 29.4a,y (5/17) 31.3a,y (5/16)
  1. 1In the fluralaner group dogs were treated once orally on day 0
  2. 2In the selamectin/sarolaner group cats and dogs were treated on day 0 and again between days 28–30 and between days 56–60
  3. 3Geometric mean numbers of fleas recovered in two intermittent light flea traps averaged within households
  4. 4{(Day 0 geometric mean animal area flea counts – day x geometric mean animal area flea counts) / day 0 geometric mean animal area flea counts)} × 100
  5. a,bGeometric mean trap flea counts in a column with unlike letter superscripts are significantly different (Day 21; P=0.032; │t│ = 2.18)
  6. x,yGeometric mean trap flea counts in a row with unlike letter superscripts are significantly different from day 0 (P < 0.001; │t│ ≥ 5.57)
  7. a,bPercent of flea- free traps in a column with like letter superscripts are not significantly different (P > 0.069; Fisher’s exact test).
  8. x,yPercent of flea- free traps in a row with unlike letter superscripts are significantly different from day 0 (P < 0.020; Fisher’s exact test)
  9. a,bPercent of flea- free homes in a column with unlike letter superscripts are significantly different (P < 0.021; Fisher’s exact test)
  10. x,yPercent of flea- free homes in a row with unlike letter superscripts are significantly different from day 0 (P < 0.046; Fisher’s exact test)