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Table 3 Fleas caught in intermittent-light flea traps in naturally infested homes in Florida before and after treatment of all dogs and cats in the homes with either a single administration of fluralaner or three consecutive monthly administrations of sarolaner (dogs) and selamectin (cats)

From: In-home assessment of either topical fluralaner or topical selamectin for flea control in naturally infested cats in West Central Florida, USA

Treatment group

Days post-treatment

  

0

7

14

21

28–30

40–45

56–60

82–86

Fluralaner1

20 homes on study

         

Geomean flea count3

32.4a,x

6.3a,y

7.2a,y

1.6b,y

0.5a,y

0.2a,y

0.1a,y

0.04a,y

Range

(5–183)

(0–113)

(0–156)

(0–19)

(0–6)

(0–5)

(0–1)

(0–1)

% control4

 

80.4

77.9

95.0

98.4

99.4

99.8

99.9

% (#) homes with 0 fleas in traps

0.0a,x (0/20)

10.5a,x (2/19)

20.0a,x (4/20)

30.0a,y (6/20)

70.0a,y (14/20)

85.0a,y (17/20

90.0a,y (18/20)

95.0a,y (19/20)

% (#) homes with no fleas (traps, cats or dogs)

0.0a,x (0/20)

15.0a,x (3/20)

15.0a,x (3/20)

30.0b,y (6/20)

60.0b,y (12/20)

75.0b,y (15/20)

80.0b,y (16/20)

95.0b,y (19/20)

Selamectin/Sarolaner2

18 homes on study

Geomean flea count3

28.0a,x

4.7a,y

4.8a,y

4.2a,y

1.4a,y

0.04a,y

0.4a,y

0.4a,y

Range

(5–152)

(0–195)

(0–93)

(0–22)

(0–1)

(0–14)

(0–39)

(0–12)

% control4

 

83.1

82.7

85.0

95.1

99.9

98.8

98.5

% (#) homes with 0 fleas in traps

0.0a,x (0/18)

16.7a,x (3/18)

17.6a,x (3/17)

22.2a,x (4/18)

44.4a,y (8/18)

94.1a,y (16/17)

82.4a,y (14/17)

68.8a,y (11/16)

% (#) homes with no fleas (traps, cats or dogs)

0.0a,x (0/18)

5.6a,x (1/18)

16.7a,x (3/18)

0.0a,x (0/18)

5.6a,x (1/18)

23.5a,y (4/17)

29.4a,y (5/17)

31.3a,y (5/16)

  1. 1In the fluralaner group dogs were treated once orally on day 0
  2. 2In the selamectin/sarolaner group cats and dogs were treated on day 0 and again between days 28–30 and between days 56–60
  3. 3Geometric mean numbers of fleas recovered in two intermittent light flea traps averaged within households
  4. 4{(Day 0 geometric mean animal area flea counts – day x geometric mean animal area flea counts) / day 0 geometric mean animal area flea counts)} × 100
  5. a,bGeometric mean trap flea counts in a column with unlike letter superscripts are significantly different (Day 21; P=0.032; │t│ = 2.18)
  6. x,yGeometric mean trap flea counts in a row with unlike letter superscripts are significantly different from day 0 (P < 0.001; │t│ ≥ 5.57)
  7. a,bPercent of flea- free traps in a column with like letter superscripts are not significantly different (P > 0.069; Fisher’s exact test).
  8. x,yPercent of flea- free traps in a row with unlike letter superscripts are significantly different from day 0 (P < 0.020; Fisher’s exact test)
  9. a,bPercent of flea- free homes in a column with unlike letter superscripts are significantly different (P < 0.021; Fisher’s exact test)
  10. x,yPercent of flea- free homes in a row with unlike letter superscripts are significantly different from day 0 (P < 0.046; Fisher’s exact test)