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Table 4 Owner assessment of pruritus using a visual analogue scale (PVAS) for cats in homes naturally infested with fleas before and after treatment with either a single topical dose of fluralaner or three consecutive topical treatments with selamectin

From: In-home assessment of either topical fluralaner or topical selamectin for flea control in naturally infested cats in West Central Florida, USA

Treatment group Days post-treatment
0 7 14 21 28–30 40–45 56–60 82–86
Fluralaner1 # Cats 31 30 30 30 31 31 31 31
Mean PVAS Score3 5.9a,x 2.6a,y 1.9a,y 1.1b,y 1.2b,y 1.0a,y 1.1a,y 0.9a,y
SD 2.31 1.93 1.61 1.40 1.70 1.32 1.71 0.96
Range (1.1–10) (0.0–8.2) (0.0–5.2) (0.0–5.0) (0.0–6.3) (0.0–5.1) (0–6.7) (0.0–2.7)
% Reduction4   56.0 68.0 80.7 79.7 82.7 81.7 84.3
Selamectin2 # Cats 29 28 28 29 28 26 27 26
Mean PVAS Score3 6.6a,x 3.1a,y 2.7a,y 2.9a,y 2.6a,y 1.3a,y 1.6a,y 1.6a,y
SD 2.58 1.09 2.12 2.40 2.31 1.46 1.92 2.12
Range (0.3–10) (1.0–5.1) (0.0–8.0) (0.2–8.8) (0.0–9.3) (0.0–4.7) (0.0–7.5) (0.0–6.7)
% Reduction4   53.6 58.9 56.6 60.6 80.9 76.2 76.5
  1. 1In the fluralaner group cats were treated once topically on day 0 (Bravecto® Topical solution; Merck Animal Health, Madison, NJ, USA)
  2. 2In the selamectin group cats were treated on day 0 and once between days 28–30 and 56–60 (Revolution®; Zoetis, Whippany, NJ, USA)
  3. 3Arithmetic mean pruritus scores as assessed by cat owners using a PVAS scoring sheet
  4. 4{(Day 0 arithmetic mean PVAS score – day x arithmetic mean PVAS score) / day 0 arithmetic mean PVAS score)} × 100
  5. a,bArithmetic mean PVAS scores in a column with unlike letter superscripts are significantly different (P < 0.005; │t│ ≥ 2.882)
  6. x,yArithmetic mean PVAS scores in a row with unlike letter superscripts are significantly different from day 0 (P < 0.001; │t│≥ 8.680)