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Fig. 5 | Parasites & Vectors

Fig. 5

From: Modelling the impact of insecticide-based control interventions on the evolution of insecticide resistance and disease transmission

Fig. 5

The potential impact of resistance on single-insecticide control interventions. The legend on each panel gives the percentage of decreased survival caused by the intervention for each genotype. The blue line shows the resistant allele frequency over time and the black line shows the number of female adult mosquitoes. The rapid decline in adult population size post-intervention shows that the magnitude of the resistance phenotype was not sufficient to prevent a population crash (although the smaller, resistant population were sufficient to allow malaria transmission; see Table 5 and main text for details). Resistance was assumed to be dominant, interventions started with a resistance allele frequency of 50% and the three genotypes in Hardy-Weinberg equilibrium. Abbreviations: IRS, indoor residual spraying; ITN, insecticide-treated net; SS, the homozygous sensitive genotype; SR, the heterozygous sensitive/resistant genotype; RR, the homozygous resistant genotype

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