Genetic diversity of merozoite surface protein-1 C-terminal 42 kDa of Plasmodium falciparum (PfMSP-142) may be greater than previously known in global isolates

Table 3 Recombination events in global PfMSP-1₄₂. The Ra, Rb and Rm were estimated excluding the sites containing alignment gaps or those segregating for three nucleotides

Allele type	Country (No. of sequences)	Ra	Rb	Rm
MAD20	Myanmar (n = 37)	0.0134	16.4	4
	Thailand (n = 29)	0	0.001	1
	Philippines (n = 24)	0.0004	0.5	0
	PNG (n = 44)	0.0028	3.4	2
	SI (n = 17)	0	0.001	0
	Vanuatu (n = 48)	0	0.001	0
	Ghana (n = 23)	0.0340	41.6	4
	Tanzania (n = 51)	0.0444	54.3	4
K1	Myanmar (n = 18)	0.0363	43.3	0
K1	Thailand (n = 12)	0.0083	9.9	0
RO33	Myanmar (n = 14)	0.0035	4.3	0
	Thailand (n = 33)	0.0028	3.4	1
	Philippines (n = 19)	0.0028	3.4	0
	PNG (n = 33)	0	0.001	1
	SI (n = 24)	0	0.001	0
	Vanuatu (n = 43)	0	0.001	0
	Ghana (n = 10)	0.0187	22.8	2
	Tanzania (n = 20)	0.0439	53.5	3

Abbreviations: Ra recombination parameter between adjacent sites, Rb recombination parameter for entire gene, Rm minimum number of recombination events between adjacent sites, PNG Papua New Guinea, SI Solomon Islands

ISSN: 1756-3305