TY - JOUR AU - Jaenson, Thomas G. T. AU - Petersson, Erik H. AU - Jaenson, David G. E. AU - Kindberg, Jonas AU - Pettersson, John H.-O. AU - Hjertqvist, Marika AU - Medlock, Jolyon M. AU - Bengtsson, Hans PY - 2018 DA - 2018/08/29 TI - The importance of wildlife in the ecology and epidemiology of the TBE virus in Sweden: incidence of human TBE correlates with abundance of deer and hares JO - Parasites & Vectors SP - 477 VL - 11 IS - 1 AB - Tick-borne encephalitis (TBE) is one tick-transmitted disease where the human incidence has increased in some European regions during the last two decades. We aim to find the most important factors causing the increasing incidence of human TBE in Sweden. Based on a review of published data we presume that certain temperature-related variables and the population densities of transmission hosts, i.e. small mammals, and of primary tick maintenance hosts, i.e. cervids and lagomorphs, of the TBE virus vector Ixodes ricinus, are among the potentially most important factors affecting the TBE incidence. Therefore, we compare hunting data of the major tick maintenance hosts and two of their important predators, and four climatic variables with the annual numbers of human cases of neuroinvasive TBE. Data for six Swedish regions where human TBE incidence is high or has recently increased are examined by a time-series analysis. Results from the six regions are combined using a meta-analytical method. SN - 1756-3305 UR - https://doi.org/10.1186/s13071-018-3057-4 DO - 10.1186/s13071-018-3057-4 ID - Jaenson2018 ER -