Table 2 Summary of carbohydrate-binding proteins of Anaplasma recognizing tick or host receptors. The carbohydrate-binding proteins from Anaplasma are listed together with the recognized molecule from the vector or the host. Glycoproteins or glycans are listed as the recognized molecules depending on the available information

MSP1a (MSP1 complex)

Vector binding partner: Unknown receptor in IDE8 tick cells

[189, 190]

Unknown molecule

Vector binding partner: Core α 1,3-fucose glycoprotein

[203]

Unknown adhesin-like molecule

Host binding partner: 1,3-Fuc and Sia in sialyl Lewis X, PSGL-1 in human neutrophils

[199, 200]

Unknown adhesin-like molecule

Host binding partner: 1,3-Fuc and Sia in sialyl Lewis X, PSGL-1 in murine neutrophils

[199]

Unknown adhesin-like molecule

Host binding partner: 1,3-Fuc and Sia in sialyl Lewis X, PSGL-1 in human myeloid HL-60 cells

[197, 201]

Unknown molecule of A. phagocytophilum NCH-1 strain

Host binding partner: 1,3-fucose in murine bone marrow-derived mast cells (BMMCs), murine peritoneal mast cells

[198]

Unknown molecule of A. phagocytophilum NCH-1 strain

Host binding partner: α 1,3-Fuc in human skin-derived mast cells

[198]

AmOmpA

Host binding partner: α2,3-sialylated and α1,3-fucosylated glycan of the sialyl Lewis x in myeloid cells

[182]

AmOmpA

Host binding partner: α2,3-sialylated and α1,3-fucosylated glycan of the 6- sulfo-sialyl Lewis x in endothelial cells

[180, 182]

AmOmpA

Host binding partner: α2,3-sialylated, α2,6-sialylated, α1,3-fucosylated glycan receptors in human and murine myeloid HL-60 cells, 6- sulpho-sialyl Lewis x in endothelial cells

[180,181,182]

Unknown

Host binding partner: α1,3-fucose

[203]