Table 5 TBEV protein glycosylation overview. List of TBEV proteins and their functions. Identified or predicted N-linked glycosylation sites are listed as well. NetNGlyc 1.0 Server was used for N-linked glycosylation site prediction

Structural

C

Capsid protein; forming of nucleocapsid

None

prM/M

Envelope protein; E protein chaperone

N32

[265, 302]

E

Envelope protein; binding and fusion

N154, N361

[263,264,265]

Non-structural

NS1

Replication

Predicted: N85, N207

NS2A

Assembly, replication

None

NS2B

NS3 serine-protease cofactor

None

NS3

Serine-protease, helicase, replication RNA triphosphatase

Predicted: N160, N499, N555

NS4A

Assembly, replication

None

NS4B

Assembly, induction of membrane rearrangements

Predicted: N188

NS5

Methyltransferase, RNA-dependent RNA polymerase

Predicted: N18, N175, N215