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Table 1 Spleen weight (g) of male mice in control and Acanthamoeba spp. infected groups after 8, 16 and 24 days post-infection (dpi)

From: Changes in the immune system in experimental acanthamoebiasis in immunocompetent and immunosuppressed hosts

Parameter/group Group A (n = 10) Group C (n = 6) Group AS (n = 10) Group CS (n = 6) Kruskal-Wallis test
Total spleen weight AM ± SD 0.06 ± 0.03a 0.07 ± 0.008a 0.08 ± 0.06b 0.10 ± 0.01b H = 29.81, df = 2, P = 0.001
Median 0.07 0.07 0.1 0.1
Range 0.02–0.15 0.06–0.09 0.01–0.20 0.1–0.15
8 dpi AM ± SD 0.05 ± 0.02c 0.07 ± 0.01c 0.11 ± 0.04 0.10 ± 0.02 H = 22.78, df = 3, P = 0.001
Median 0.06 0.07 0.10 0.10
Range 0.03– 0.07 0.06–0.08 0.1–0.2 0.1–0.15
16 dpi AM ± SD 0.05 ± 0.02d 0.07 ± 0.01d 0.04 ± 0.06e 0.10 ± 0.0e H = 15.36, df = 3, P = 0.01
Median 0.06 0.07 0.01 0.10
Range 0.02–0.07 0.06–0.08 0.01–0.20 0.10–0.10
24 dpi AM ± SD 0.08 ± 0.03f 0.08 ± 0.01 0.09 ± 0.03f 0.10 ± 0.0 H = 13.79, df = 3, P = 0.01
Median 0.08 0.08 0.10 0.10
Range 0.05–0.15 0.07–0.09 0.01–0.10 0.10–0.10
  1. aP ≤ 0.03 for the significance of difference A vs C (Mann-Whitney U-test, U = 311),
  2. bP ≤ 0.04 for the significance of difference AS vs CS (Mann-Whitney U-test, U = 297)
  3. cP ≤ 0.05 for the significance of difference A vs C (Mann-Whitney U-test, U = 30)
  4. dP ≤ 0.02 for the significance of difference A vs C (Mann-Whitney U-test, U = 41)
  5. eP ≤ 0.02 for the significance of difference AS vs CS (Mann-Whitney U-test, U = 42.5)
  6. fP ≤ 0.02 for the significance of difference A vs AS (Mann-Whitney U-test, U = 72)
  7. Abbreviations: Group A, immunocompetent infected group; Group C, immunocompetent control group; Group AS immunosuppressed infected group; Group CS, immunosuppressed non-infected group; AM, arithmetic mean; SD, standard deviation