Skip to main content

Advertisement

Table 4 Immunophenotyping results in % (spleen) of Acanthamoeba spp.-infected immunosuppressed mice and control mice with low immunity

From: Changes in the immune system in experimental acanthamoebiasis in immunocompetent and immunosuppressed hosts

Parameter/group    Group AS (n = 10) Group CS (n = 6) Mann-Whitney U-test
CD3+/CD4+ (T lymphocytes) (%) 8 dpi AM ± SD 22.67 ± 0.13 24.47 ± 0.09 U = 16, P = 0.53
Median 22.87 25.57
Range 18.62–26.69 21.51–26.73
16 dpi AM ± SD 28.87 ± 0.05 27.51 ± 0.20 U = 15, P = 0.09
Median 25.09 25.78
Range 23.11–26.19 22.27–36.82
24 dpi AM ± SD 25.17 ± 0.43 16.68 ± 0.18 U = 21, P = 0.05
Median 22.17 17.35
Range 14.67–43.74 12.04–20.34
CD3+/CD8+ (%) 8 dpi AM ± SD 5.25 ± 0.14 6.16 ± 0.37 U = 14, P = 0.83
Median 5.21 6.03
Range 4.44–6.28 4.23–9.89
16 dpi AM ± SD 7.40 ± 0.05 4.55 ± 0.24 U = 25, P = 0.01
Median 7.51 4.19
Range 6.83–7.94 3.39–6.36
24 dpi AM ± SD 4.23 ± 0.60 4.10 ± 0.17 U = 19, P = 0.21
Median 5.54 3.83
Range 0.05–7.45 3.35–5.16
CD3+/CD4+/CD8+ (DP %) 8 dpi AM ± SD 1.13 ± 0.19 1.82 ± 0.29 U = 21, P = 0.09
Median 1.18 1.87
Range 0.83–1.35 0.96–2.36
16 dpi AM ± SD 1.52 ± 0.24 1.61 ± 0.38 U = 13, P = 0.99
Median 1.66 1.61
Range 0.98–1.94 1.17–2.6
24 dpi AM ± SD 2.71 ± 0.89 1.32 ± 0.35 U = 19, P = 0.03
Median 1.63 1.07
Range 1.1–7.47 0.96–2.03
CD3+/CD4-/CD8- (DN %) 8 dpi AM ± SD 0.12 ± 0.21 0.21 ± 0.18 U = 24, P = 0.02
Median 0.12 0.23
Range 0.1–0.16 0.16–0.24
16 dpi AM ± SD 0.14 ± 0.10 0.09 ± 0.65 U = 20, P = 0.14
Median 0.14 0.09
Range 0.11–0.17 0.03–0.18
24 dpi AM ± SD 0.16 ± 0.59 0.11 ± 0.26 U = 19, P = 0.15
Median 0.22 0.11
Range 0.004–0.24 0.07–0.13
  1. Abbreviations: Group A, immunocompetent infected group; Group C, immunocompetent control group; Group AS immunosuppressed infected group; Group CS, immunosuppressed non-infected group; AM, arithmetic mean; SD, standard deviation DP, CD3+/CD4+/CD8+ double-positive T cells; DN, CD3+CD4−CD8− double-positive T cells