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Table 3 Polymorphisms in malic enzyme (me) gene

From: Exploiting genetic polymorphisms in metabolic enzymes for rapid screening of Leishmania infantum genotypes

Zymodeme Strain/isolate GenBank ID 106 204 327 329 390 507 586 762 843 919 1182 1287 1620
MON-1 MHOM/FR/78/LEM75 DQ449701.1 G C C T T T C C C G A C G
MON-1 MHOM/ES/1993/PM1 DQ449703.1 . . . . . . . . . . . . .
MON-1 MHOM/FR/1995/LPN114 DQ449702.1 . . . . . . . . . . . . .
MON-1 MHOM/PT/2000/IMT260 DQ449706.1 . . . . . . . . . . . . .
MON-1 MHOM/FR/1997/LSL29 DQ449704.1 . . . . . . . . . . . . .
MON-1 MHOM/ES/1986/BCN16 DQ449705.1 . . . . . . . . . . . . .
MON-1 MHOM/BL/67/ITMAP263 KU175196.1 . . . . . . . . . . . .
MON-1 MHOM/TN/80/IPT1 MF375413 . . . G . . . .
MON-1 MHOM/FR/78/LEM75 MF375414 . . . . . . . .
MON-1 Isolate 31U MF375415 . . . . . . . .
MON-1 Isolate 49u MF375416 . . . . . . .
MON-1 Isolate 10816 MF375417 . . . . . . . .
MON-1 Isolate 791 MF375418 . . . . . . . .
MON-1 Isolate V2921 MF375419 . .
MON-11 MHOM/FR/1980/LEM189 DQ449714.1 . . . . G . . . . . . . .
MON-24 MHOM/DZ/82/LIPA59 MF375420 T . G G G . . T
MON-29 MHOM/ES/82/BCN1 MF375421 . M G G G . . .
MON-29 MHOM/FR/1996/LEM3249 DQ449707.1 . . . . G . . . . . . . .
MON-72 MHOM/IT/86/ISS218 MF375422 . . . . . . . . . . .
MON-78 MHOM/MT/1985/BUCK DQ449715.1 . . G G G . . . A C T .
MON-81 MHOM/SD/1962/3Sa DQ449718.1 . . G G G A G . A . . .
MON-98 MHOM/GR/2001/GH6 DQ449728.1 . . . . G . . . . . . . .
MON-98 MCAN/GR/2001/GD8 DQ449729.1 . . . . G . . . . . . . .
MON-98 MHOM/GR/2003/GH15 DQ449730.1 . . . . G . . . . . . . .
MON-98 MHOM/GR/2003/GH16 DQ449731.1 . . . . G . . . . . . . .
MON-98 MHOM/GR/2003/GH18 DQ449732.1 . . . . G . . . . . . . .
MON-98 MHOM/GR/2003/GH20 DQ449733.1 . . . . G . . . . . . . .
MON-98 MHOM/GR/2004/GD17 DQ449734.1 . . . . G . . . . . . . .
MON-183 MHOM/ES/1991/LEM2298 DQ449708.1 . . . . G . . . . . . . .
MON-188 MHOM/IT/1993/ISS800 DQ449722.1 . T . G G G . . T A . . .
MON-198 MHOM/ES/1988/LLM175 DQ449719.1 . . . . G . . . . . . . .
MON-199 MHOM/ES/1992/LLM373 DQ449720.1 A . . G G G . . . . C . .
MON-201 MHOM/IT/93/ISS822 MF375423 . . . . . . . . . . . .
MON-228 MHOM/IT/1994/ISS1036 DQ449721.1 . . . . G . . . . . . . S
MON-267 MHOM/SD/1997/LEM3472a DQ449723.1 . . . G G G . . . A . . .
MON-309 ITOB/TR/2005/CUK2 EU545253.1 . T . K G G . . Y A . . .
MON-309 MHOM/TR/2005/CUK1 EU545252.1 . T . G G G . . T A . . .
ni ITOB/TR/2007/CUK10 EU545254.1 . T . K G G . . Y A . . .
non-MON-1 MHOM/TR/2000/OG-VL EU545255.1 . . . . G . . . . . . . .
ni Isolate RRR-B DQ449727.1 . . . . G . . . . . . . .
  1. Zymodeme sequences obtained in this study are in bold
  2. Abbreviation: ni not indicated
  3. Key: . consensus sequence, – sequence not available
  4. aInitially assigned to L. infantum and successively designated L. donovani [18]