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Table 3 Percent of cats infested with ticks on Day 0 that were free of ticks at subsequent visits

From: Field effectiveness and safety of fluralaner plus moxidectin (Bravecto® Plus) against ticks and fleas: a European randomized, blinded, multicenter field study in naturally-infested client-owned cats

Treatment group Cats free of ticks (%)
Visit 2 Visit 3 Visit 4 Visit 5
Per protocol population
 Fluralaner + moxidectin 96.1 92.8 93.4 94.1
 Fipronil 88.3 89.6 81.8 92.2
 Lower 97.5% one-sided confidence limita 0.0008 -0.0456 0.0294 -0.0534
P-value for non-inferiorityb <0.0001 <0.0001 <0.0001 <0.0001
 Intent to treat population
 Fluralaner + moxidectin 96.5 91.8 93.4 93.3
 Fipronil 86.1 88.2 83.1 91.6
 Lower 97.5% one-sided confidence limita 0.0293 -0.0403 0.0215 -0.0530
P-value for non-inferiorityb <0.0001 <0.0001 <0.0001 <0.0001
  1. aLower 97.5% one-sided confidence limit was well above the non-inferiority limit of -0.15. If the lower confidence limit was above 0, superiority was concluded
  2. bFarrington-Manning method