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Table 2 The top 30 differentially expressed GO terms between T. gondii-infected and uninfected cats

From: Transcriptomic insights into the early host-pathogen interaction of cat intestine with Toxoplasma gondii

GO category GO name Gene number FDR corrected P-value
Cluster 1 Cluster 2 Cluster 3 Cluster 4 Cluster 5 Cluster 6
Biological process Carbohydrate_metabolic_process 22 28 4 27 1 0 2.03E-04
Cellular amino acid metabolic process 20 8 8 6 0 0 0.014098
tRNA metabolic process 20 5 5 3 0 0 0.04415
Cellular component Extracellular region 30 27 38 6 11 2 3.84E-04
Extracellular matrix 7 7 14 0 3 0 0.018194
Extracellular matrix component 1 4 10 0 1 0 0.014935
Myosin complex 6 2 8 0 1 0 0.021049
Extracellular region part 13 11 19 0 5 0 0.022411
Molecular function Catalytic activity 194 93 182 19 40 5 4.44E-16
Hydrolase activity 95 52 93 15 13 3 3.02E-10
Ion binding 137 49 117 6 23 1 0.044804
Nucleotide binding 94 16 48 2 11 0 0.008417
Small molecule binding 99 19 55 3 12 0 0.001499
Anion binding 92 18 49 1 10 1 0.020323
Carbohydrate derivative binding 83 16 42 3 10 0 0.026838
Pyrophosphatase activity 52 6 24 0 4 0 0.030815
Nucleoside-triphosphatase activity 51 6 23 0 4 0 0.043152
Oxidoreductase activity 47 14 41 3 10 1 2.03E-04
Cofactor binding 23 9 23 2 8 0 0.001491
Cargo receptor activity 4 3 4 0 0 0 0.001611
Chemokine receptor binding 5 0 1 0 4 0 0.002826
Coenzyme binding 15 4 12 1 3 0 0.008153
G-protein coupled receptor binding 5 0 1 0 4 0 0.012537
Motor activity 12 2 9 0 1 0 0.012498
Metalloexopeptidase activity 0 2 2 3 0 0 0.013723
Metallocarboxypeptidase activity 0 2 1 3 0 0 0.036387
Tetrapyrrole binding 4 4 7 1 4 0 0.029038
Cytokine activity 5 0 1 0 4 0 0.033712
Peroxiredoxin activity 4 0 1 0 0 0 0.037208
Adenylylsulfate kinase activity 2 1 2 0 0 0 0.044538