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Table 2 The top 30 differentially expressed GO terms between T. gondii-infected and uninfected cats

From: Transcriptomic insights into the early host-pathogen interaction of cat intestine with Toxoplasma gondii

GO category

GO name

Gene number

FDR corrected P-value

Cluster 1

Cluster 2

Cluster 3

Cluster 4

Cluster 5

Cluster 6

Biological process

Carbohydrate_metabolic_process

22

28

4

27

1

0

2.03E-04

Cellular amino acid metabolic process

20

8

8

6

0

0

0.014098

tRNA metabolic process

20

5

5

3

0

0

0.04415

Cellular component

Extracellular region

30

27

38

6

11

2

3.84E-04

Extracellular matrix

7

7

14

0

3

0

0.018194

Extracellular matrix component

1

4

10

0

1

0

0.014935

Myosin complex

6

2

8

0

1

0

0.021049

Extracellular region part

13

11

19

0

5

0

0.022411

Molecular function

Catalytic activity

194

93

182

19

40

5

4.44E-16

Hydrolase activity

95

52

93

15

13

3

3.02E-10

Ion binding

137

49

117

6

23

1

0.044804

Nucleotide binding

94

16

48

2

11

0

0.008417

Small molecule binding

99

19

55

3

12

0

0.001499

Anion binding

92

18

49

1

10

1

0.020323

Carbohydrate derivative binding

83

16

42

3

10

0

0.026838

Pyrophosphatase activity

52

6

24

0

4

0

0.030815

Nucleoside-triphosphatase activity

51

6

23

0

4

0

0.043152

Oxidoreductase activity

47

14

41

3

10

1

2.03E-04

Cofactor binding

23

9

23

2

8

0

0.001491

Cargo receptor activity

4

3

4

0

0

0

0.001611

Chemokine receptor binding

5

0

1

0

4

0

0.002826

Coenzyme binding

15

4

12

1

3

0

0.008153

G-protein coupled receptor binding

5

0

1

0

4

0

0.012537

Motor activity

12

2

9

0

1

0

0.012498

Metalloexopeptidase activity

0

2

2

3

0

0

0.013723

Metallocarboxypeptidase activity

0

2

1

3

0

0

0.036387

Tetrapyrrole binding

4

4

7

1

4

0

0.029038

Cytokine activity

5

0

1

0

4

0

0.033712

Peroxiredoxin activity

4

0

1

0

0

0

0.037208

Adenylylsulfate kinase activity

2

1

2

0

0

0

0.044538