Fig. 5
MCC950 altered pro-fibrotic markers in primary HSCs isolated from mice infected with S. japonicum. The primary HSCs were isolated from different group mice. The mRNA and protein expressions of α-SMA and Collagen I were determined by RT-PCR (a) and western blot (b), respectively. The representative images and quantification are shown. Three independent experiments were performed, and one representative figure is shown. *P < 0.05, **P < 0.01, ***P < 0.001 vs N; a, bP < 0.05, aa, bbP < 0.01 vs SJ