A randomized, blinded, controlled trial to assess sand fly mortality of fluralaner administered orally in dogs

Parasites & Vectors

Table 2 Negative binomial mixed model results including treatment group, experimental day and their interaction as fixed effects and dog as random effect. The incidence rate ratio (IRR) represents the increase in the rate of incidence compared with control per day

Explanatory variable^a	IRR^b	95% CI	P-value
Day -7	0.75	0.09–4.85	0.77
Day 3	32.87	4.09–263	0.001**
Day 17	76.06	8.20–705	0.0002**
Day 31	95.85	8.92–1029	0.0002**
Day 45	10.66	1.43–79	0.02*
Day 73	2.50	0.34–18	0.36

^aThe explanatory variables used control group at each corresponding day after treatment as baseline comparison (Pr(>|z|))
^bIncidence rate ratio, as the ratio between the incidence rate in control group and the incidence rate for each treatment group, at the corresponding experimental day after treatment
*Significance level at α = 0.05
**Significance level at α = 0.001

ISSN: 1756-3305