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Table 1 Toxicity of Bacillus thuringiensis svar. israelensis (IPS-82) and its protoxins to Bti-selected Ae. aegypti larvae

From: Long-term exposure of Aedes aegypti to Bacillus thuringiensis svar. israelensis did not involve altered susceptibility to this microbial larvicide or to other control agents

Samplea No. of larvae LC50 (95% CI)b RRc LC90 (95% CI)b RRc
Bti
 Rocke 1620 0.008 (0.007–0.009) 1.0 0.026 (0.021–0.036) 1.0
 RecBti
 F1 1480 0.013 (0.011–0.016) 1.6 0.030 (0.024–0.048) 1.2
 F5 1380 0.022 (0.018–0.028) 2.8 0.069 (0.048–0.143) 2.7
 F10 1080 0.018 (0.015–0.020) 2.3 0.049 (0.039–0.070) 1.9
 F15 1380 0.012 (0.010–0.013) 1.5 0.029 (0.024–0.038) 1.1
 F20 1680 0.009 (0.007–0.010) 1.1 0.024 (0.021–0.030) 0.9
 F25 1680 0.007 (0.006–0.009) 0.9 0.026 (0.022–0.035) 1.0
 F30 1680 0.012 (0.010–0.013) 1.5 0.024 (0.022–0.029) 0.9
Cry11Aa
 Rocke 1080 0.162 (0.121–0.210) 1.0 1.506 (0.909–3.525) 1.0
 Rocked 1260 0.436 (0.338–0.666) 1.0 2.470 (1.650–8.576) 1.0
 RecBti
 F2 1600 0.121 (0.099–0.145) 0.7 0.512 (0.396–0.727) 0.3
 F5 1440 0.217 (0.183–0.256) 1.3 0.754 (0.571–1.052) 0.5
 F10 1440 0.498 (0.369–0.642) 3.1 4.515 (2.717–12.965) 3.0
 F15 1260 0.459 (0.365–0.568) 2.8 2.923 (2.020–5.116) 1.9
 F20 1260 0.672 (0.540–0.846) 4.1 4.677 (2.965–9.055) 3.1
 F25d 1260 0.653 (0.472–0.924) 1.5 nd nd
 F30d 2400 1.662 (1.203–2.400) 3.8 nd nd
Cry4Ba
 Rocke 1080 0.331 (0.209–0.492) 1.0 nd nd
 RecBti      
 F2 1280 0.694 (0.483–0.978) 2.1 nd nd
 F5 1200 0.402 (0.304–0.508) 1.2 nd nd
 F10 1200 0.707 (0.435–1.265) 2.1 nd nd
 F15 2100 0.570 (0.396–0.806) 1.7 nd nd
 F20 1200 0.424 (0.276–0.610) 1.3 nd nd
 F25 1260 0.701 (0.487–0.989) 2.1 nd nd
 F30 1260 0.882 (0.575–1.426) 2.7 nd nd
  1. Abbreviation: nd not determined
  2. aRockefeller (Rocke) reference strain and the RecBti selected strain
  3. bLethal concentrations (mg/l) for 50% and 90% of third-instar larvae exposed for 24 h (mean and 95% confidence intervals, CI)
  4. cResistance ratio between the LC for the test strain and that for the reference strain
  5. dReference used to determine RR for F25 and F30