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Fig. 1 | Parasites & Vectors

Fig. 1

From: Comparative bioinformatic analysis suggests that specific dauer-like signalling pathway components regulate Toxocara canis development and migration in the mammalian host

Fig. 1

Life-cycle and dauer signalling orthologues of Caenorhabditis elegans, Toxocara canis and Ascaris suum. Schematic representation of the life-cycles of C. elegans (a), T. canis (b) and A. suum (c). Specifically, the third-stage larvae (L3s) of T. canis can arrest in the tissues for years, and can be reactivated in the female dog (bitch) in the last trimester of pregnancy and then migrate to uterus or mammary glands (post partum), leading to transplacental or transmammary transmission to offspring (grey arrows). d Dauer signalling gene orthologues in T. canis and A. suum are indicated (in blue) and compared to C. elegans genes. Increased numbers of orthologues are identified in T. canis and/or A. suum (orange). Orthologues not inferred for T. canis and/or A. suum are indicated in grey

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