Table 2 Relationship between average T90 and the concentrations of the drugs tested
Drug | Concentration (μg/ml) | Average T90 ± SD | Kruskal-Wallis rank sum test | Spearman’s rank correlation | |||
|---|---|---|---|---|---|---|---|
χ 2 | df | P-value | rho | P-value | |||
DMSO (0.1%) | 11.08 ± 0.35 | – | – | – | – | – | |
FLBZ | 0.05 | 5.10 ± 0.1 | 18.974 | 5 | 0.001944 | -0.970 | <0.0001 |
0.1 | 5.05 ± 0.08 | ||||||
0.5 | 3.15 ± 0.66 | ||||||
1 | 1.97 ± 0.06 | ||||||
10 | 1.10 ± 0.14 | ||||||
HFLBZ | 0.05 | 10.46 ± 0.18 | 19.043 | 5 | 0.001887 | -0.974 | <0.0001 |
0.1 | 10.20 ± 0.35 | ||||||
0.5 | 7.21 ± 0.63 | ||||||
1 | 5.03 ± 0.36 | ||||||
10 | 1.90 ± 0.14 | ||||||
RFLBZ | 0.05 | 5.52 ± 1.01 | 18.506 | 5 | 0.002374 | -0.934 | <0.0001 |
0.1 | 5.93 ± 0.33 | ||||||
0.5 | 4.87 ± 0.28 | ||||||
1 | 3.54 ± 0.25 | ||||||
10 | 2.85 ± 0.21 | ||||||