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Table 1 IC50 values of tribendimidine and praziquantel against newly excysted metacercariae and adult Opisthorchis felineus worms

From: A study of tribendimidine effects in vitro and in vivo on the liver fluke Opisthorchis felineus

Compound NEM Adults
Tribendimidine (TBN) (μM) 0.23 ± 0.059 0.19 ± 0.1
Praziquantel (PZQ) (μM) 0.98 ± 0.18 0.47 ± 0.05
  1. For calculation of the half-maximal inhibitory concentration (IC50), we tested the following concentrations of compounds: 0.001, 0.01, 0.1, 1, 10 and 100 μM. Data are presented as IC50 values ± standard error (R package drc 3.0-1)
  2. Abbreviation: NEM, newly excysted metacercariae