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Table 2 Worm burden reduction values obtained after treatment of hamsters harboring O. felineus with tribendimidine or praziquantel

From: A study of tribendimidine effects in vitro and in vivo on the liver fluke Opisthorchis felineus

  Number of animals Mean no. of worms ± SD WBR (%) Mean EPG ± SD ERR (%)
Treatment of chronic infection (3 months)
 Control 13 33 ± 10 1863 ± 1006
 TBN, 400 mg/kg 5 7 ± 4 76 927 ± 620 51.0
 PZQ, 400 mg/kg 11 8 ± 5 77.2 nd nd
Treatment of acute infection (1 month)
 Control1 5 19 ± 2 863 ± 279
 Control2 6 34 ± 9 nd
 TBN1, 400 mg/kg 5 2 ± 4 90 299 ± 244 65.4
 PZQ2, 400 mg/kg 7 8 ± 6 76.5 nd nd
Treatment of acute infection (15 days)
 TBN1, 400 mg/kg 5 2 ± 2 90.7 463 ± 281 46.3
  1. Superscript numbers denote data relative to the corresponding control group
  2. Abbreviations: TBN, tribendimidine; PZQ, praziquantel; SD, standard deviation, WBR, worm burden reduction rate, EPG, eggs per gram of feces, ERR, egg reduction rates, nd, not determined