From: A study of tribendimidine effects in vitro and in vivo on the liver fluke Opisthorchis felineus
Number of animals | Mean no. of worms ± SD | WBR (%) | Mean EPG ± SD | ERR (%) | |
---|---|---|---|---|---|
Treatment of chronic infection (3 months) | |||||
Control | 13 | 33 ± 10 | – | 1863 ± 1006 | – |
TBN, 400 mg/kg | 5 | 7 ± 4 | 76 | 927 ± 620 | 51.0 |
PZQ, 400 mg/kg | 11 | 8 ± 5 | 77.2 | nd | nd |
Treatment of acute infection (1 month) | |||||
Control1 | 5 | 19 ± 2 | – | 863 ± 279 | – |
Control2 | 6 | 34 ± 9 | – | nd | – |
TBN1, 400 mg/kg | 5 | 2 ± 4 | 90 | 299 ± 244 | 65.4 |
PZQ2, 400 mg/kg | 7 | 8 ± 6 | 76.5 | nd | nd |
Treatment of acute infection (15 days) | |||||
TBN1, 400 mg/kg | 5 | 2 ± 2 | 90.7 | 463 ± 281 | 46.3 |