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Table 2 Study 1. Frequency of major histopathological changes recorded in the organs of mice inoculated with ~30 A. abstrusus third-stage larvae each by histological examination of half organs at intervals after inoculation (two mice per time point)

From: Mice as paratenic hosts of Aelurostrongylus abstrusus

Days after inoculation

Number of mice demonstrating histopathological alterations in the

Brain

Spleen

Liver

Kidneys

Lungs

Diaphragm

Multifocal encephalitis with perivascular cuffing of small lymphocytes

Multifocal lymphocytic encephalitis

Glial nodules

Multifocal extramedullar haematopoiesis

Extramedullar haematopoiesis

Multifocal mononuclear cell infiltration of cortical and medullary interstitium

Multifocal lymphocytic peribronchial inflitration

Thickening of serous membrane through mixed cell infiltration

Lymphocytic diaphragmitis

10

2/2

2/2

0/2

1/2

1/2

1/2

1/2

0/2

0/2

20

2/2

2/2

1/2

1/2

1/2

1/2

2/2

0/2

0/2

30

2/2

2/2

1/2

1/2

2/2

1/2

2/2

1/2

1/2

45

1/2

1/2

2/2

0/2

0/2

0/2

0/2

1/2

1/2

60

2/2

2/2

2/2

0/2

0/2

0/2

0/2

2/2

2/2