Bioabsorption and effectiveness of long-lasting permethrin-treated uniforms over three months among North Carolina outdoor workers

Table 1 Summary of metabolite urine concentration and three-month average estimated permethrin quantities from 12 participants^a

		Median metabolite urine concentrations (μg/l)				3-month average estimated permethrin (from Eqn 1)
Metabolite	Metabolite molecular weight	Baseline	1 week	1 month	3 months	3-month average^a	Dose fraction in urine^b	Urine concentration (μg/l)	Dosage (μg/kg)
3-PBA	214	1.6	46.7	47.1	15.3	36.4	0.46	36.4	3.1
Cis-DCCA	209	< 0.5	22.1	29.7	10.2	20.7	0.43	20.7	3.2
Trans-DCCA	209	< 0.6	57.4	58.8	21.6	45.9	0.26	45.9	4.3

^aMean of 1 week, 1 month and 3-month average measurements, across all participants; human excretion of metabolites following a known oral dose were measured by Ratelle et al. [18]
^bHuman excretion of metabolites following a known oral dose were measured as in Ratelle et al. [18]

ISSN: 1756-3305