From: The treatment of sarcoptic mange in wildlife: a systematic review
Treated species and reference | No. of animals treated | Severitya | Treatmentb | Duration of post-treatment monitoring | |||
---|---|---|---|---|---|---|---|
Drug(s) administered | Dose & delivery method | No. of doses | Treatment interval between doses | ||||
American black bear (Ursus americanus), Van Wick et al. (2018) [21] | 1 | Severe | a) Fluralaner; b) Lactated Ringer’s solution; c) Hydrogenated iron | a) 44 mg/kg PO; b) 40 ml/kg SC; c) 10 mg/kg IM | a) 1; b) 1; c) 1 | na | 13 weeks |
Mara (Dolichotis caviae), Kim et al. (2015) [25] | 2/16 (i.e. clinically affected individuals) | Moderate | a) Amitraz; b) Prednisolone | a) 0.025% wash; b) 2 ml IM | a) 4; b) 4 | a) 7 days; b) 7 days | Â |
16/16 (i.e. colony-wide treatment) | Mild to moderate | a) Ivermectin; b) Prednisolone | a) 400 µg/kg SC; b) 2 ml IM | a) 4; b) 4 | a) 7 days; b) 7 days | 104 weeks | |
Raccoon dog (Nyctereutes procyonoides), Kido et al. (2014) [27] | 68 | Moderate to severe | Ivermectin | 400 µg/kg SC | 2 | 14 days | 18 weeks on average |
157 | Moderate to severe | a) Ivermectin; b) Cephalexin; c) Lactated Ringer’s solution | a) 400 µg/kg SC; b) 20 mg/kg PO; c) Intravenous | a) 3; b) 14; c) 1 | a) 14 days; b) 12 hours; c) na | 18 weeks on average | |
Southern hairy-nosed wombat (Lasiorhinus latrifrons), Ruykys et al. (2013) [24] | 2/5 (i.e. captive wombats) | Severe | Ivermectin | 200 µg/kg SC | 1 | na | 7–10 weeks, depending on the animal |
African buffalo (Syncerus caffer), Munang’Andu et al. (2010) [26] | 77 | Mild to severe | Ivermectin | 200 µg/kg SC | 4 | 30 days | 6 weeks |
Roe deer (Capreolus capreolus), Menzano et al. (2008) [20] | 3 | Moderate to severe | Ivermectin | 300 µg/kg SC | 3 | 15 days | 52 weeks |
Bare-nosed wombat (Vombatus ursinus), Skerratt et al. (2003) [28] | 2/7 (i.e. Experiment one) | Mild to severe | a) Ivermectin; b) Procaine penicillin; c) Benzaine penicillin | a) 300 µg/kg SC; b) 15 mg/kg IM; c) 11 mg/kg IM | a) 3; b) 1; c) 1 | a) 10 days; b) na; c) na | 22 weeks |
 | 7/7 (i.e. Experiment two) | Mild to severe | a) Ivermectin; b) Procaine penicillin; c) Benzaine penicillin | a) 300 µg/kg SC; b) 15 mg/kg IM; c) 11 mg/kg IM | a) 3; b) 1; c) 1 | a) 10 days; b) na; c) na | 8 weeks |
 | 3/7 (i.e. wombats whose mange recurred in Experiment two) | Mild | Ivermectin | 300 µg/kg SC | 3 | 10 days | 18 weeks |
Iberian ibex (Capra pyrenaica), Leon-Vizcaino et al. (2001) [23] | 3 | Moderate | Ivermectin | 400 µg/kg SC | 1 | na | 8 weeks |
3 | Moderate | Ivermectin | 400 µg/kg SC or superficial IM by rifle dart | 1 | na | 8 weeks | |
3 | Moderate | Ivermectin | 200 µg/kg SC | 1 | na | 8 weeks | |
3 | Severe | Ivermectin | 200 µg/kg SC | 2 | 14 days | 6 weeks | |
3 | Severe | Ivermectin | 400 µg/kg SC | 2 | 14 days | 6 weeks | |
17 | None to mild | a) Phoxim; b) Ivermectin | a) 500 mg/l topical spray; b) 400 µg/kg SC | a) 1; b) 1 | na | 45 weeks | |
32 | Mild to moderate | a) Phoxim; b) Ivermectin | a) 500 mg/l topical spray; b) 200–400 µg/kg SC or superficial IM by rifle dart | a) 1; b) 3 | a) na; b) 14 days | 45 weeks | |
Chamois (Rupricapra pyrenaica), Lavin et al. (2000) [51] | 2 | Mild to moderate | Ivermectin | 200 µg/kg SC | 2 | 15 days | 2 weeks |
Red fox (Vulpes vulpes), Little et al. (1998) [52] | 5 | Severe | Ivermectin | 400 µg/kg SC | 2 | 14 days | 8–15 weeks, depending on the animal |