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Table 1 Repellent effect of DEET, permethrin, carvacrol, geraniol, cuminaldehyde and cinnamaldehyde on Anopheles gambiae from reference strains, the susceptible Kisumu strain (Kis), the pyrethroid-resistant strain (KdrKis) and the OP-resistant strain (AcerKis)

From: Insecticide resistance modifies mosquito response to DEET and natural repellents

Product

Concentration (µl/cm2)

Kis strainab

KdrKis strainab

AcerKis strainab

Permethrin

0.010

0.0 (0.0–4.9)

4.3 (0.0–10.6)

2.7 (0.0–9.6)

0.100

6.3 (0.0–14.0)

11.0 (2.9–19.1)

8.0 (0.0–16.7)

DEET

0.010

0.0 (0.0–1.4)

20.1 (9.2–31.0)

11.9 (2.6–21.2)

0.100

15.0 (5.2–24.7)

29.2 (17.4–40.9)

85.7 (77.6–93.8)*

Carvacrol

0.001

9.4 (1.7–17.0)

11.2 (3.1–19.3)

5.7 (0.0–13.5)

0.014

36.6 (25.0–48.2)

42.0 (30.1–53.8)

0.0 (0.0–3.6)*

Geraniol

0.002

5.1 (0.0–13.0)

3.1 (0.0–9.5)

22.1 (9.4–34.8)

0.023

50.5 (38.0–63.1)

41.0 (28.9–53.1)

9.7 (0.0–20.2)*

Cuminaldehyde

0.003

1.6 (0.0–4.7)

24.7 (12.6–36.8)*

8.5 (0.6–16.5)

0.030

25.4 (14.3–36.5)

52.9 (41.0–64.9)*

47.0 (35.2 - 58.8)

Cinnamaldehyde

0.008

16.5 (7.8–25.3)

36.2 (24.0–48.4)

37.7 (24.9–50.5)

0.079

43.0 (32.1–54.0)

82.1 (74.2–90.0)*

53.1 (40.9–65.3)

  1. aProportion of escaping mosquitoes as a percentage corrected with the negative control to compare strains by pairs (confidence interval)
  2. bPairwise comparison of proportion was done using Fisher’s test with the Holm’s sequential Bonferroni correction method. Values in bold lettering are significantly different from the non-treated control. Values followed by an asterisk (*) are significantly different from the Kis strain