Skip to main content

Table 3 Toxic effects of DEET, permethrin, carvacrol, geraniol, cuminaldehyde and cinnamaldehyde on Anopheles gambiae from reference strains, the susceptible Kisumu strain (Kis), the pyrethroid-resistant strain KdrKis and the OP-resistant strain AcerKis

From: Insecticide resistance modifies mosquito response to DEET and natural repellents

Product

Concentration (µl/cm2)

Kis strainab

KdrKis strainab

AcerKis strainab

Permethrin

0.010

93.8 (89.7–97.8)

2.7 (0.0–9.6)*

66.1 (53.7–78.5)*

0.100

96.8 (96.8–96.8)

63.2 (49.8–76.5)*

100.0 (100.0–100.0)

DEET

0.010

2.6 (0.0–8.6)

0.0 (0.0–1.2)

0.0 (0.0–0.0)

0.100

98.2 (98.2–98.2)

20.9 (9.7–32.0)*

96.6 (96.6–96.6)

Carvacrol

0.001

4.3 (0.0–9.0)

3.3 (0.0–9.8)

0.0 (0.0–0.0)

0.014

0.0 (0.0–0.0)

0.0 (0.0–0.0)

0.0 (0.0–0.0)

Geraniol

0.002

0.0 (0.0–3.6)

1.7 (0.0–4.9)

0.0 (0.0–4.0)

0.023

0.0 (0.0–3.5)

3.1 (0.0–7.3)

1.2 (0.0–9.3)

Cuminaldehyde

0.003

0.0 (0.0–0.0)

1.3 (0.0–5.5)

0.0 (0.0–0.0)

0.030

11.1 (3.4–18.9)

3.8 (0.0–9.9)

30.9 (17.4–44.5)*

Cinnamaldehyde

0.008

0.0 (0.0–0.0)

0.0 (0.0–0.0)

0.2 (0.0–3.8)

0.079

45.9 (32.9–58.8)

93.9 (87.2–100.6)*

89.9 (81.9–97.9)*

  1. aProportion of dead mosquitoes in percentage corrected with the negative control to compare strains by pairs
  2. bPairwise comparison of proportion was done using Fisher’s test with the Holm’s sequential Bonferroni correction method. Values in bold lettering are significantly different from the non-treated control. Values followed by an asterisk (*) are significantly different from the Kis strain