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Fig. 3 | Parasites & Vectors

Fig. 3

From: Plant Hsp90 is a novel adjuvant that elicits a strong humoral and cellular immune response against B- and T-cell epitopes of a Toxoplasma gondii SAG1 peptide

Fig. 3

Cytokine production by spleen cell cultures from C57BL/6 immunized mice. Two weeks after last immunization, splenocytes from 5 mice per group were cultured, and the cytokine production in cell supernatants after rSAG1 stimulation was measured by ELISA. Values for IFN-γ (a) and IL-10 (b) at 72 h are expressed as mean ± SEM. Results represent one of two similar experiments. IFN-γ: ***P < 0.001 NbHsp90.3-SAG1HC vs PBS, NbHsp90.3 and SAG1m groups. IL-10: *P < 0.05, NbHsp90.3 vs NbHsp90.3-SAG1HC group; **P < 0.01, NbHsp90.3 vs PBS group; ***P < 0.001, SAG1m vs NbHsp90.3-SAG1HC group; ****P < 0.0001 SAG1m vs PBS group. Statistical analysis was performed by two-way analysis of variance (ANOVA) using Tukey’s multiple comparisons test

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