Fig. 2
From: Total serum IgD from healthy and sick dogs with leishmaniosis
a Specific L. infantum antibodies levels in healthy non-infected, healthy infected and sick dogs classified based on LeishVet clinical staging. b Total serum IgD concentrations in healthy non-infected, healthy infected and sick dogs classified based on LeishVet clinical staging. White circles represent individual data of each animal, boxes represent minimum and maximum values of quartiles, the bands inside represent the second quartile (median). Statistical results of L. infantum specific antibodies by ELISA: Group 1 (healthy non-infected) < Group 2 (healthy infected) (Mann-Whitney U-test: Z = -4.46, P < 0.0001), Group 1 (healthy non-infected) < Group 3 (sick) (Mann-Whitney U-test: Z = −9.59, P < 0.0001), Group 2 (healthy infected) < Group 3 (sick) (Mann-Whitney U-test: Z = -7.84, P < 0.0001), mild stages (I and IIa) < severe stages (IIb, III and IV) (Mann-Whitney U-test: Z = -3.07, P = 0.002), stage I < stage IIa (Mann-Whitney U-test: Z = -4.45, P < 0.0001), stage I < stage IIb (Mann-Whitney U-test: Z = -3.07, P = 0.002), stage I < Stage III (Mann-Whitney U-test: Z = -3.25, P = 0.001), stage I < stage IV (Mann-Whitney U-test: Z = -2.85, P = 0.004), stage IIa < stage IV (Mann-Whitney U-test: Z = -2.59, P = 0.01)