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Fig. 4 | Parasites & Vectors

Fig. 4

From: Immunosuppressive effects of tick protein RHcyst-1 on murine bone marrow-derived dendritic cells

Fig. 4

RHcyst-1 inhibits T cell activation and cytokine production. BMDCs were stimulated with OVA-CD4 (a) and OVA-CD8 (b) peptide with or without RHcyst-1 treatment, respectively. The above BMDCs were co-cultured with T cells from spleen for another 72 h. The levels of IL-2, TNF-α and IFN-γ were measured by flow cytometry. Student’s t-test was applied and a P-value < 0.05 was considered statistically significant. ** indicates P < 0.01; bars represent the mean of three independent experiments ± SD

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