Identification and characterization of Pv50, a novel Plasmodium vivax merozoite surface protein

Parasites & Vectors

Table 1 Prevalence (% positive), 95% confidence intervals and mean fluorescence of intensity of IgG responses to Plasmodium vivax 50 in human patients and healthy individual serum samples

Antigen	No. of patient samples			MFI	95% CI (%)	No. of healthy samples			MFI	95% CI (%)	P-value^c
Antigen	Positive	Negative	Total (%)^a	MFI	95% CI (%)	Positive	Negative	Total (%)^b	MFI	95% CI (%)	P-value^c
Pv50	48	64	112 (42.9)	9501	41.2–60.8	5	75	80 (6.2)	2830	91.2–98.9	<0.0001

^aSensitivity: % positive in patient samples
^bSpecificity: % negative in healthy samples
^cDifferences in the total IgG prevalence for each antigen between vivax patients and healthy individuals were calculated with the Mann-Whitney test; P < 0.05 was considered as statistically significant
Abbreviations: MFI, mean fluorescence intensity; CI, confidence interval

ISSN: 1756-3305