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Fig. 1 | Parasites & Vectors

Fig. 1

From: Drug transporter and oxidative stress gene expression in human macrophages infected with benznidazole-sensitive and naturally benznidazole-resistant Trypanosoma cruzi parasites treated with benznidazole

Fig. 1

Effects of benznidazole on the intracellular viability of BZ-sensitive and BZ-resistant T. cruzi strains in human THP-1 MΦ cells. a Intracellular survival of CL Brener (sensitive) and Colombiana (resistant) T. cruzi strain amastigotes treated with BZ (13 µM). b Photomicrographs of Giemsa-stained THP-1 MФ cells treated with 13 µM BZ containing amastigotes of sensitive and resistant T. cruzi strains (arrow). c Parasitic load in the different groups described below. The results represent the average of two independent experiments + SEM. Significant differences were determined by two-way ANOVA, followed by Bonferroni’s multiple comparison test, *P < 0.05, **P < 0.01, and ***P < 0.001. Scale bars: 20 μm

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