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Fig. 3 | Parasites & Vectors

Fig. 3

From: Aedes aegypti saliva impairs M1-associated proinflammatory phenotype without promoting or affecting M2 polarization of murine macrophages

Fig. 3

Macrophage spare respiratory capacity is decreased in the presence of Ae. aegypti SGE. Thioglycolate-elicited peritoneal macrophages were collected and cultured in Seahorse plates as described in Methods. Mitochondrial function was compared in basal conditions and after the sequential addition of oligomycin (1 μg/ml), CCCP (4.5 μM) and rotenone/antimycin A (1 μM each) on a Seahorse flux analyzer. Basal and maximal OCR are expressed as the mean ± SEM. *P < 0.05 versus control group (cells incubated with medium only)

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Parasites & Vectors

ISSN: 1756-3305

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