Fig. 4

Contrasting correlation of thoracic cavity alternatively activated macrophage numbers and adult worm burden and MF counts. Spearman correlation of the total thoracic cavity RELMα-positive macrophage numbers and adult worm burden (a, b) and peripheral blood microfilariae (MF) counts (c, d) at 71 (a, c) and 119 days (b, d) post-L. sigmodontis-infection in IL-4R^−/− (green dots), dblGATA (red dots), IL-5^−/− (blue dots), IL-4R^−/−/IL-5^−/− (orange dots) mice and wildtype controls (black dots). Data shown in a, c are pooled from two independent experiments at 71 dpi with 10–16 mice per group. Remaining panels (b, d) are from one experiment at 119 dpi with 6–10 mice per group