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Table 1 Demographic characteristics of the siblings grouped in 71 phratries, the remaining controls and the full cohort

From: A retrospective study on the influence of siblings’ relatedness in Bolivian patients with chronic Chagas disease

Variable Siblings (n = 53) (71 groups) (%) Control (n = 685) (299 groups) (%) P-value siblings vs controls Cohort (n = 833) (%) P-value siblings vs cohort
Country of origin
 Argentina 3 (1.96) 15 (2.18) 0.865 18 (2.16) 0.875
 Bolivia 144 (94.11) 640 (93.43) 0.757 784 (94.11) 1.000
 Brazil 0 2 (0.29) 0.505 2 (0.24) 0.544
 Chile 0 1 (0.14) 0.141 1 (0.12) 0.668
 Colombia 0 2 (0.29) 0.505 2 (0.24) 0.544
 Ecuador 1 (0.65) 4 (0.58) 0.919 5 (0.60) 0.942
 El Salvador 0 2 (0.29) 0.505 2 (0.24) 0.544
 Honduras 3 (1.96) 5 (0.72) 0.152 8 (0.90) 0.240
 Paraguay 0 6 (0.87) 0.247 6 (0.70) 0.299
 Spain 2 (1.30) 1 (0.14) 0.028* 3 (0.36) 0.132
 Venezuela 0 2 (0.29) 0.505 2 (0.24) 0.544
Sex
 Female 104 (67.97) 457 (66.71) 0.765 561 (67.34) 0.878
 Male 49 (32.02) 223 (32.55) 0.899 272 (32.65) 0.878
Mean age (years) 42 44   44  
Pre-treatment PCR 112 (73.20) 495 (73.26) 0.988 607 (72.86) 0.931
 Positive 45 (40.17) 200 (29.19) 0.008* 245 (29.41) 0.008*
Kushnir 142 (92.81) 637 (93.00) 0.934 779 (93.51) 0.749
 K 0 119/142 (83.80) 539/637 (84.61) 0.803 658/779 (84.44) 0.841
 K 1 18/142 (12.67) 77/637 (12.08) 0.840 95/779 (12.19) 0.868
 K 2 2/142 (1.40) 12/637 (1.88) 0.686 14/779 (1.79) 0.734
 K 3 3/142 (2.11) 9/637 (1.41) 0.525 12/779 (1.54) 0.609
Barium enema 128 (83.66) 553 (80.72) 0.399 681 (81.75) 0.572
 Pathologic 24 (18.75) 119 (17.37) 0.685 143 (21.00) 0.527
Esophagogram 109 (71.24) 421 (61.45) 0.023* 530 (63.62) 0.069
 Pathologic 6/109 (5.55) 26/421 (3.79) 0.322 32/530 (6.03) 0.818
Treatment 100 (65.35) 441 (64.37) 0.819 541 (64.94) 0.922
 Benznidazole 91/100 (91) 409/441 (93) 0.392 500/541 (92.00) 0.678
 Posaconazole 9/100 (9) 32/441 (7.2) 0.445 41/541 (7.57) 0.544
Rash (benznidazole) 16/91 (17.58) 88/409 (21.51) 0.279 104/500 (20.80) 0.3628
  1. *P < 0.05 (statistically significant differences)
  2. Abbreviations: n, number of patients; PCR, polymerase chain reaction