Bacteriology (bacterial load and virulence factors) | ||||
---|---|---|---|---|
E. coli (virulence factors) | Cl. perfringens (type; toxin) | |||
Day of infection | 1st dol | 3rd dol | 1st dol | 3rd dol |
Litters 4 days post-infection | ||||
++ − +++ a [fimH; iucD (2 litters)] | ++ - +++a [fimH, papC, iucD, cnf1] | + [A, beta 2] | +++ [A, beta 2] | |
Individual piglets (1st dol: n = 1+1, 3rd dol: n = 7) | ||||
Diarrhoeic piglet(s), toltrazuril treated | (+) [fimH; iucD] | ++ - +++a [fimH, papC, iucD, cnf1] | Negative | + − +++ [A, beta 2] |
Matched healthy control | (+) [fimH] | Not done | Negative | Not done |
Sows ante partum | ||||
++ − +++a [fimH, papC, astA, iucD, cnf1] | Not done | Negative | Not done |