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Fig. 5 | Parasites & Vectors

Fig. 5

From: Contribution of tissue transglutaminase to the severity of hepatic fibrosis resulting from Schistosoma japonicum infection through the regulation of IL-33/ST2 expression

Fig. 5

Suppression of tTG activity decreases the expression level of IL-33/ST2. a The protein expression levels of IL-33 and ST2 in mice liver homogenates detected by Western blotting are displayed on the left panel, and the result of semi-quantitative analysis is shown on the right panel. GAPDH was used as a loading control. b, c The protein expression levels and location of IL-33 (B) and ST2 (C) in mice liver tissue were determined by IHC assay (200× and 400× left, scale-bar: 50 μm), and the result of semi-quantitative analysis of the protein signal using modified H score is shown on the right panel. Data are presented as the mean ± SD. All experiments were performed twice or thrice. Red arrows indicate the Sj eggs (t-test, **P = 0.0014, ****P < 0.0001)

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