Fig. 4
From: Investigating immune responses to parasites using transgenesis
Transgenic P. berghei parasite expressing a circumsporozoite protein induces a strong antibody production and protection efficiency. Briefly, the transgenic malaria parasite lines infect the RBC of C57BL/6 mice and leads to the activation of B cells and IFN-γ production by CD4+ T cells. Passive transfer of antibodies to naïve recipient mice confers protection through opsonization process