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Table 3 ROC curve analyses of metabolites to identify HAE patients

From: Deciphering the metabolic perturbation in hepatic alveolar echinococcosis: a 1H NMR-based metabolomics study

Metabolites Sensitivity (%) Specificity (%) AUC (95%)
Serum
 Glutamate 100.00 88.89 0.924 (0.802–1.000)
 Valine 94.44 88.89 0.920 (0.804–1.000)
 Leucine 77.78 88.89 0.920 (0.801–0.981)
 Phenylalanine 88.89 94.44 0.914 (0.782–1.000)
 Creatine 83.33 88.89 0.870 (0.731–0.981)
 Isoleucine 83.33 72.22 0.852 (0.716–0.951)
 Lysine 83.33 77.78 0.849 (0.665–0.974)
 Formate 77.78 88.89 0.833 (0.676–0.960)
 Betaine 77.78 83.33 0.824 (0.684–0.948)
 Serine 83.33 77.78 0.824 (0.676–0.941)
 1-methylhistidine 72.22 77.78 0.785 (0.627–0.914)
 Tyrosine 83.33 72.22 0.782 (0.609–0.924)
 Lactate 83.33 77.78 0.762 (0.590–0.911)
 Glutamine 66.67 83.33 0.716 (0.532–0.873)
Urine
 Glutamate 77.78 77.78 0.864 (0.714–0.957)
 Creatinine 83.33 88.89 0.816 (0.645–0.952)
 p-hydroxyphenylacetate 72.22 88.89 0.815 (0.611–0.955)
 3-hydroxybutyrate 77.78 72.22 0.793 (0.619–0.914)
 Malate 72.22 83.33 0.781 (0.614–0.920)
 Glycolate 66.67 77.78 0.772 (0.572–0.900)
 γ-aminobutyrate 72.22 72.22 0.769 (0.586–0.903)
 3-methylhistidine 72.22 77.78 0.765 (0.591–0.920)