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Fig. 4 | Parasites & Vectors

Fig. 4

From: A novel praziquantel solid lipid nanoparticle formulation shows enhanced bioavailability and antischistosomal efficacy against murine S. mansoni infection

Fig. 4

Hepatic (a) and intestinal (b) tissue egg-load in infected mice treated with M-PZQ or SLN-PZQ. Mice were sacrificed 14 days after treatment. Data are presented as the means ± SEM. n = 6–8 mice per group. Number in parentheses represents the percentages of egg reduction vs infected untreated control. *Significant difference vs infected untreated control at P < 0.05. Significant difference between SLN-PZQ and M-PZQ treatment at P < 0.05. Abbreviations: SLN-PZQ, solid lipid nanoparticle praziquantel; M-PZQ, market praziquantel

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