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Table 2 List of identified differentially abundant tick proteins, showing spot number, UniProt identifier, protein name, function annotated from BLAST similarity search, localisation assigned by PSORT algorithm, ProteinLynx reliability score, number of matched peptides and sequence coverage, theoretical and experimental molecular weights/isoelectric points, and if the protein is more abundant (↑) or less abundant (↓) upon Rickettsia infection

From: Comparative proteomics of the vector Dermacentor reticulatus revealed differentially regulated proteins associated with pathogen transmission in response to laboratory infection with Rickettsia slovaca

Spot Accession Description Function Localisation PLGS score Peptides/ coverage (%) Theoretical MW (kDa)/pI Experimental MW (kDa)/pI Regulation
1482 L7LTU1 Put. tick salivary serpin, Rhipicephalus pulchellus Serin protease inhibitor Secreted 417 9/17.5 44/5.8 48/5.5
1489 L7LTU1 Put. tick salivary serpin, Rhipicephalus pulchellus Serin protease inhibitor Secreted 711 6/12.0 44/5.8 48/5.7
1897 L7LRE8 Put. glycine rich protein, Rhipicephalus pulchellus Salivary gland peptide Secreted 7161 15/24.9 38/9.0 42/9.5
1945 L7LRE8 Put. glycine rich protein, Rhipicephalus pulchellus Salivary gland peptide Secreted 3053 14/24.9 38/9.0 41/9.3
2791 A0A131XM62 Put. ML domain protein, Hyalomma excavatum Salivary lipid interaction Secreted 969 3/14.8 20/7.9 24/7.0
5046 A0A131XS44 Secreted protein, Hyalomma excavatum Cuticle Secreted 531 4/19.5 14/4.7 14/4.1
5154 A0A023FST8 Put. large gyy 1, glycine-proline rich Amblyomma cajennense Salivary gland peptide Secreted 4046 5/29.8 14/9.8 14/9.5
3035 B7QNW6 Put. secreted protein, Ixodes scapularis Immunomodulation Secreted 138 2/21.4 24/8.1 21/5.1
1601 G3MND3 Phosphoglycerate kinase, Amblyomma maculatum Glycolysis Cytoplasm 2573 15/33.7 44/8.2 47/8.5
1602 A0A131XNT2 Put. ubiquinone oxidoreductase ndufa9/39 kda sb., Hyalomma excavatum Mitochondrial complex Mitochondrion 5391 13/27.9 44/9.2 47/9.5
1808 A0A147BGN0 Put. eukaryotic translation initiation factor 4 γ, Ixodes ricinus Translation initiation factor Cytoplasm/ nucleus 112 3/41.8 17/4.7 44/9.6
1976 L7M642 Put. zinc-binding oxidoreductase, Rhipicephalus pulchellus Quinone oxidereductase/ETC Cytoplasm 421 3/12.7 36/8.7 41/8.4
2715 A0A023FRH0 Put. heat shock protein, Amblyomma cajennense HSP20 domain containining Cytoplasm/ nucleus 403 3/11.9 22/6.2 26/5.5
2818 B7SP22 Put. glutathione S-transferase, Dermacentor variabilis Detoxification Cytoplasm 2052 9/36.3 26/8.2 24/8.3
2707 A0A131YF71 Troponin I protein, Rhipicephalus appendiculatus Muscle contraction Cytoplasm 217 3/11.5 23/10.3 26/9.8
305 A0A1E1X279 Put. myosin class I heavy chain, Amblyomma aureolatum Actin filament binding Cytoplasm/ nucleus 1397 28/16.4 222/5.7 100/5.2
2833 A0A023FIT8 Put. myosin regulatory light chain, Amblyomma cajennense Muscle contraction Cytoplasm 159 4/17.1 20/4.2 24/4.4
2917 A0A131XKV8 Put. ATP synthase sb. o mitochondrial-like protein, Hyalomma excavatum ATP synthesis/ proton transport Mitochondrion 3087 10/23.7 23/10.1 23/9.9
3025 B7Q9B4 Put. membrane protein, Ixodes scapularis Porin Cell membrane 227 2/51.2 9/9.7 21/6.3
3871 A0A131YSI2 Ubiquitin-conjugating enzyme E2 L3, Rhipicephalus appendiculatus Proteolysis Cytoplasm/ mitochondrion 2337 7/55.8 18/9.1 17/9.3
4628 A0A023GDJ7 Histone H4, Amblyomma triste DNA binding Nucleus 2630 11/60.2 11/11.8 13/8.7
  1. Abbreviations: put., putative; sb., subunit; ETC, electron transport chain