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Table 2 List of identified differentially abundant tick proteins, showing spot number, UniProt identifier, protein name, function annotated from BLAST similarity search, localisation assigned by PSORT algorithm, ProteinLynx reliability score, number of matched peptides and sequence coverage, theoretical and experimental molecular weights/isoelectric points, and if the protein is more abundant (↑) or less abundant (↓) upon Rickettsia infection

From: Comparative proteomics of the vector Dermacentor reticulatus revealed differentially regulated proteins associated with pathogen transmission in response to laboratory infection with Rickettsia slovaca

Spot

Accession

Description

Function

Localisation

PLGS score

Peptides/ coverage (%)

Theoretical MW (kDa)/pI

Experimental MW (kDa)/pI

Regulation

1482

L7LTU1

Put. tick salivary serpin, Rhipicephalus pulchellus

Serin protease inhibitor

Secreted

417

9/17.5

44/5.8

48/5.5

↑

1489

L7LTU1

Put. tick salivary serpin, Rhipicephalus pulchellus

Serin protease inhibitor

Secreted

711

6/12.0

44/5.8

48/5.7

↑

1897

L7LRE8

Put. glycine rich protein, Rhipicephalus pulchellus

Salivary gland peptide

Secreted

7161

15/24.9

38/9.0

42/9.5

↑

1945

L7LRE8

Put. glycine rich protein, Rhipicephalus pulchellus

Salivary gland peptide

Secreted

3053

14/24.9

38/9.0

41/9.3

↑

2791

A0A131XM62

Put. ML domain protein, Hyalomma excavatum

Salivary lipid interaction

Secreted

969

3/14.8

20/7.9

24/7.0

↑

5046

A0A131XS44

Secreted protein, Hyalomma excavatum

Cuticle

Secreted

531

4/19.5

14/4.7

14/4.1

↓

5154

A0A023FST8

Put. large gyy 1, glycine-proline rich Amblyomma cajennense

Salivary gland peptide

Secreted

4046

5/29.8

14/9.8

14/9.5

↓

3035

B7QNW6

Put. secreted protein, Ixodes scapularis

Immunomodulation

Secreted

138

2/21.4

24/8.1

21/5.1

↑

1601

G3MND3

Phosphoglycerate kinase, Amblyomma maculatum

Glycolysis

Cytoplasm

2573

15/33.7

44/8.2

47/8.5

↑

1602

A0A131XNT2

Put. ubiquinone oxidoreductase ndufa9/39 kda sb., Hyalomma excavatum

Mitochondrial complex

Mitochondrion

5391

13/27.9

44/9.2

47/9.5

↑

1808

A0A147BGN0

Put. eukaryotic translation initiation factor 4 γ, Ixodes ricinus

Translation initiation factor

Cytoplasm/ nucleus

112

3/41.8

17/4.7

44/9.6

↓

1976

L7M642

Put. zinc-binding oxidoreductase, Rhipicephalus pulchellus

Quinone oxidereductase/ETC

Cytoplasm

421

3/12.7

36/8.7

41/8.4

↑

2715

A0A023FRH0

Put. heat shock protein, Amblyomma cajennense

HSP20 domain containining

Cytoplasm/ nucleus

403

3/11.9

22/6.2

26/5.5

↑

2818

B7SP22

Put. glutathione S-transferase, Dermacentor variabilis

Detoxification

Cytoplasm

2052

9/36.3

26/8.2

24/8.3

↓

2707

A0A131YF71

Troponin I protein, Rhipicephalus appendiculatus

Muscle contraction

Cytoplasm

217

3/11.5

23/10.3

26/9.8

↑

305

A0A1E1X279

Put. myosin class I heavy chain, Amblyomma aureolatum

Actin filament binding

Cytoplasm/ nucleus

1397

28/16.4

222/5.7

100/5.2

↓

2833

A0A023FIT8

Put. myosin regulatory light chain, Amblyomma cajennense

Muscle contraction

Cytoplasm

159

4/17.1

20/4.2

24/4.4

↑

2917

A0A131XKV8

Put. ATP synthase sb. o mitochondrial-like protein, Hyalomma excavatum

ATP synthesis/ proton transport

Mitochondrion

3087

10/23.7

23/10.1

23/9.9

↑

3025

B7Q9B4

Put. membrane protein, Ixodes scapularis

Porin

Cell membrane

227

2/51.2

9/9.7

21/6.3

↑

3871

A0A131YSI2

Ubiquitin-conjugating enzyme E2 L3, Rhipicephalus appendiculatus

Proteolysis

Cytoplasm/ mitochondrion

2337

7/55.8

18/9.1

17/9.3

↓

4628

A0A023GDJ7

Histone H4, Amblyomma triste

DNA binding

Nucleus

2630

11/60.2

11/11.8

13/8.7

↑

  1. Abbreviations: put., putative; sb., subunit; ETC, electron transport chain