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Fig. 3 | Parasites & Vectors

Fig. 3

From: Killer yeasts exert anti-plasmodial activities against the malaria parasite Plasmodium berghei in the vector mosquito Anopheles stephensi and in mice

Fig. 3

WaF17.12-KT reduces parasitaemia in PbGFPCON infected mice. Healthy mice were inoculated using PbGFPCON-infected blood of a donor mouse previously incubated for 90 min at 25 °C with WaF17.12-KT+ (100 µg/ml KT), WaF17.12-KT+ (100 µg/ml KT) and mAbKT4, or PBS (control). Five days after inoculations, parasitaemia of the recipient mice (n = 5 per group) was evaluated and mean values ± SEM, calculated as reported in Bonkian et al. [34], are reported. The experiment was repeated twice. Statistical analysis was performed using the Mann–Whitney test (Control vs WaF17.12-KT+: U(10)v= 124, Z = 2.04228, P = 0.04136; Control vs WaF17.12-KT+ + Ab: U(10) = 83, Z = 1.790, P = 0.03673; WaF17.12-KT+ vs Ab: U(10) = 85, Z = 1.690, P = 0.03656). *P < 0.05

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