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Table 1 Diagnostic performance of the Kato-Katz method for C. sinensis infection

From: Improving diagnostic performance of the Kato-Katz method for Clonorchis sinensis infection through multiple samples

No. of smears No. of positive cases No. of negative cases Prevalence (95% CI) (%) False negative rate (%) GMEPG of the positive cases (1)a Overestimation of GMEPG (%)b GMEPG of the positive cases (2)c GMEPG of the false negative casesc
1 stool × 1 smear 45 352 11.3 (8.2–14.5) 41.6 126.4 105.2 121.2 23.8d
1 stool × 2 smears 49 348 12.3 (9.1–15.6) 36.4 119.9 94.7 100.8 26.0e
1 stool × 3 smears 55 342 13.9 (10.4–17.3) 28.6 91.0 47.8 79.0 33.1f
2 stools × 1 smear 64 333 16.1 (12.5–19.8) 16.9 95.4 55.0 96.1 6.9g
2 stools × 2 smears 73 324 18.4 (14.6–22.2) 5.2 74.1 20.3 70.2 5.7h
2 stools × 3 smears 77 320 19.4 (15.5–23.3) 0.0 61.6 0.0 61.6
  1. aOnly the available smears were calculated
  2. bThe calculation was based on the GMEPG of the positive cases (1)
  3. cAll six smears in ‘gold’ standard were calculated
  4. dt(75) = 4.39, P < 0.001, compared to the GMEPG of the positive cases (2)
  5. et(75) = 3.42, P = 0.001, compared to the GMEPG of the positive cases (2)
  6. ft(75) = 1.97, P = 0.053, compared to the GMEPG of the positive cases (2)
  7. gt(75) = 9.62, P < 0.001, compared to the GMEPG of the positive cases (2)
  8. ht(75) = 2.87, P = 0.005, compared to the GMEPG of the positive cases (2)