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Table 1 Diagnostic performance of the Kato-Katz method for C. sinensis infection

From: Improving diagnostic performance of the Kato-Katz method for Clonorchis sinensis infection through multiple samples

No. of smears No. of positive cases No. of negative cases Prevalence (95% CI) (%) False negative rate (%) GMEPG of the positive cases (1)a Overestimation of GMEPG (%)b GMEPG of the positive cases (2)c GMEPG of the false negative casesc
1 stool × 1 smear 45 352 11.3 (8.2–14.5) 41.6 126.4 105.2 121.2 23.8d
1 stool × 2 smears 49 348 12.3 (9.1–15.6) 36.4 119.9 94.7 100.8 26.0e
1 stool × 3 smears 55 342 13.9 (10.4–17.3) 28.6 91.0 47.8 79.0 33.1f
2 stools × 1 smear 64 333 16.1 (12.5–19.8) 16.9 95.4 55.0 96.1 6.9g
2 stools × 2 smears 73 324 18.4 (14.6–22.2) 5.2 74.1 20.3 70.2 5.7h
2 stools × 3 smears 77 320 19.4 (15.5–23.3) 0.0 61.6 0.0 61.6 –
  1. aOnly the available smears were calculated
  2. bThe calculation was based on the GMEPG of the positive cases (1)
  3. cAll six smears in ‘gold’ standard were calculated
  4. dt(75) = 4.39, P < 0.001, compared to the GMEPG of the positive cases (2)
  5. et(75) = 3.42, P = 0.001, compared to the GMEPG of the positive cases (2)
  6. ft(75) = 1.97, P = 0.053, compared to the GMEPG of the positive cases (2)
  7. gt(75) = 9.62, P < 0.001, compared to the GMEPG of the positive cases (2)
  8. ht(75) = 2.87, P = 0.005, compared to the GMEPG of the positive cases (2)
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