Fig. 3
Between strain analysis of abundant proteins. a Volcano plot of control mice. On the X-axis are the log2 fold differences and on the Y-axis is the − log(P) value. The black curve indicates the cutoff for statistically significant proteins with FDR of 0.05 and S0 = 0.1. The top 20 most abundant proteins are highlighted in orange. Proteins involved in the oxidative phosphorylation are highlighted in purple. b Volcano plot of infected mice. On the X-axis are the log2 fold differences and on the Y-axis is the − log(P) value. The black curve indicates the cutoff for statistically significant proteins with FDR of 0.05 and S0 = 0.1. The top 20 most abundant proteins are highlighted in orange. Proteins involved in the oxidative phosphorylation are highlighted in purple. Immune system proteins are highlighted in green. c String network analysis of differentially abundant proteins upregulated in C57BL/6J control mice when compared to CBA/Ca control mice, indicated as C57BL/6J>CBA/Ca. Proteins marked in red are part of retinol metabolism. Blue marked proteins are part of the cytochrome P450. If proteins are involved in both pathways, their representative dots are coloured half and half. d String network analysis of C57BL/6J infected mice when compared to CBA/Ca infected mice. Red proteins are part of retinol metabolism. Blue marked proteins are part of the cytochrome P450 proteins. Proteins in purple are part of the mitochondrial small ribosomal subunit. Immune system proteins are green and phagosome proteins are yellow