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Fig. 4 | Parasites & Vectors

Fig. 4

From: The liver proteome in a mouse model for Ascaris suum resistance and susceptibility: evidence for an altered innate immune response

Fig. 4

a C57BL/6J infected compared to C57BL/6J control. Volcano plot showing the differentially abundant proteins of C57BL/6J mice. On the X-axis are the log2 fold differences and on the Y-axis is the − log(P) value. The black curve indicates the cutoff for statistically significant proteins with FDR of 0.05 and S0 = 0.1. Proteins abundant in control mice are on the left of the plot and abundant proteins present in infected mice are on the right of the plot. The top 20 most abundant proteins are highlighted in orange. Immune proteins are green squares and proteins involved in the phagosome are blue circles. b Volcano polt of CBA/Ca infected compared to CBA/Ca control. On the X-axis are the log2 fold differences and on the Y-axis is the − log(P) value. The black curve indicates the cutoff for statistically significant proteins with FDR of 0.05 and S0 = 0.1. Proteins abundant in control mice ae on the left of the plot and abundant proteins present in infected mice are on the right of the plot. The top 20 most abundant proteins are highlighted orange. Immune proteins are green squares and proteins involved in the phagosome are blue circles. c C57BL/6J infected compared to C57BL/6J control. String network analysis of the proteins found to be differentially abundant in C57BL/6J infected mice when compared to C57BL/6J controls. Red is retinol metabolism. Blue is spliceosome proteins and green is complement pathway. d CBA/Ca infected compared to CBA/Ca control. Visualisation of a STRING network analysis performed on the differentially abundant proteins of CBA/Ca in infected mice when compared to CBA/Ca control mice. Proteins highlighted in red are the complement pathway

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